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Tag: Cancer: Breast

Abemaciclib + Endocrine Therapy Improves Survival in HR-Positive, HER2-Negative Early Breast Cancer

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15.8 percent lower risk for death seen with abemaciclib-ET versus ET in intent-to-treat population

Incidence Rates Increased From 2003 to 2017 for Six Cancer Types in 42 Countries

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Apart from colorectal cancer, increases in incidence were seen in both younger and older adults

Estimates of Breast CA Risk for Pathogenic Variants Vary by Family Hx

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Estimates for established pathogenic variants vary by family history and potentially modifiable risk factors

Incidence of Invasive Lobular Carcinoma Rose From 2012 to 2021

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Authors say that because survival after seven years is lower, more early detection strategies are needed

Polygenic Risk Score 313 Can Predict Risk for Breast Cancer After In Situ Disease

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Significant association seen for increasing continuous PRS313 and risk for contralateral disease after DCIS

Protein Markers of Inflammation Tied to Fatigue in Early-Stage Breast Cancer

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Positive within-person associations seen between general fatigue and TNF-α, sTNF-RII, IL-6; and between physical fatigue and TNF-α, sTNF-RII, CRP

Skipping First Mammogram Screening Increases Long-Term Breast Cancer Mortality Risk

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Higher mortality likely reflects delayed detection, not higher incidence

Elderly Patients Benefit From Screening Mammography

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Women 80 years and older with screening more likely to present with earlier-stage disease and have better survival versus unscreened women

FDA Approves Inluriyo for Advanced Breast Cancer

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Approval is for adults with ER-positive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer

Adding Molecular Breast Imaging to DBT Beneficial for Dense Breasts

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Adding MBI to digital breast tomosynthesis provided incremental cancer detection rates of 6.7 and 3.5 percent at year 1 and year 2, respectively