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Gut dysbiosis seems to affect systolic blood pressure in a rat model

Rat Study Shows Gut Dysbiosis Impacts Systolic Blood Pressure

SBP up in WKY rats gavaged with spontaneously hypertensive stroke prone rat microbiota
For older patients with hypertension

Benefits for Intensive BP Lowering in Older HTN Patients

Intensive BP control linked to reductions in MACE, cardiovascular mortality, and heart failure
Seventeen million American adults may have masked hypertension

17 Million U.S. Adults May Have Masked Hypertension

Masked hypertension more common among males, those with diabetes, older adults
Developing hypertension in very old age may provide some protection from dementia

Hypertension Onset After Age 80 May Protect Against Dementia

Association independent of antihypertensive medication use
Two leading medical organizations are recommending a less aggressive target for the treatment of hypertension in adults 60 and older who are otherwise healthy. The new clinical practice guideline was published online Jan. 17 in the Annals of Internal Medicine.

ACP, AAFP Raise BP Rx Threshold for Healthy Adults Over 60

Guideline says therapy should begin after systolic BP meets or exceeds 150 mm Hg, not 140
Use of ethanol cookstoves is associated with a reduction in diastolic blood pressure and hypertension for pregnant women in Nigeria

Use of Ethanol Cookstoves Can Lower BP, Reduce HTN

Randomized controlled trial shows reduction in diastolic BP for ethanol cookstoves
The global rate of hypertension and prehypertension rose significantly between 1990 and 2015

Global Rates of Hypertension on the Rise

And health risks may appear even at levels once considered safe, researchers contend
For adults aged 80 years and older without comorbidity

SBP <135 mm Hg Tied to Greater Mortality in Elderly With HTN

Findings in the oldest adults with hypertension and free from comorbidities
Conventional clinical trials are unable to detect clinically important heterogeneity in intensive blood pressure treatment effects

Conventional Trials Can’t Detect Heterogeneity in BP Tx Effects

Clinically important heterogeneity in intensive BP tx effect can be ID'd in sequential randomization trials
For midlife ovariectomized Long Evans rats

Duration of Estrogen Rx May Be Important Factor in Renal Health

Long-term estradiol treatment induced renal and cardiac hypertrophy, reduced glomerular filtration