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Magnetic resonance imaging is an accurate and safe tool for the detection of low levels of iron overload in patients with hereditary hemochromatosis

MRI Effectively Measures Hemochromatosis Iron Burden

MRI tested in detection of iron stores in heart, liver and spleen, and pancreas
For patients undergoing total hip arthroplasty or total knee arthroplasty

Increased BMI Protective Against Blood Transfusions

Findings among patients undergoing total hip, knee arthroplasty
For patients in intensive care units who need a catheter

Subclavian Vein Catheterization Beats Jugular, Femoral Placement

Reduces risk of blood infection, deep-vein thrombosis among critically ill
Imetelstat

Imetelstat Deemed Active in Myelofibrosis, Thrombocythemia

Responses for patients with myelofibrosis, essential thrombocythemia
An experimental blood test may one day detect the return of early-stage breast cancer months before it is revealed by computed tomography or magnetic resonance imaging

Blood Test Predicts Relapse in Early-Stage Breast Cancer

Circulating tumor DNA analysis spots stray cells months before scans detect recurrence
Daratumumab monotherapy has a favorable safety profile and encouraging efficacy in patients with heavily pretreated and refractory myeloma in a phase 1-2 trial. The results of the study were published online Aug. 26 in the New England Journal of Medicine.

Daratumumab Monotherapy Promising for Multiple Myeloma

Findings in a phase 1-2 study of patients with relapsed myeloma or relapsed/refractory myeloma
U.S. Food and Drug Administration approval of the drug Promacta (eltrombopag) has been expanded to include children 1 year and older with chronic immune thrombocytopenic purpura.

Promacta Approval Expanded for Children With Chronic ITP

Builds on recent approval for ages 6 years and up for chronic immune thrombocytopenic purpura
The International Staging System combined with chromosomal abnormalities detected by interphase fluorescent in situ hybridization after CD138 plasma cell purification and serum lactate dehydrogenase has prognostic value in newly-diagnosed multiple myeloma

Revised Staging System Prognostic for Multiple Myeloma

ISS plus chromosomal abnormalities, lactate dehydrogenase prognostic in multiple myeloma
The 2006 American Society of Clinical Oncology guidelines on use of hematopoietic colony-stimulating factors have been updated

ASCO Updates Guidelines for Colony-Stimulating Factor Use

Special article updates 2006 guidelines, including addition of tbo-filgrastim and filgrastim-sndz
Extreme exercise may trigger sepsis in people who haven't trained properly

Extreme Exercising Without Training May Trigger Sepsis

Exercise over a prolonged period of time allows endotoxins in the gut to leak into the bloodstream