Similar functional outcomes at 12 weeks post-surgery for newly diagnosed localized prostate CA
THURSDAY, July 28, 2016 (HealthDay News) — For men with newly diagnosed clinically localized prostate cancer, robot-assisted laparoscopic prostatectomy has similar functional outcomes to radical retropubic prostatectomy, according to a study published online July 26 in The Lancet.
John W. Yaxley, M.B.B.S., from the Royal Brisbane & Women’s Hospital in Australia, and colleagues conducted a randomized controlled trial involving men with newly diagnosed clinically localized prostate cancer who had chosen surgery as their treatment approach. Men were randomized to robot-assisted laparoscopic prostatectomy or radical retropubic prostatectomy (163 in each group); data were analyzed for 157 and 151 men, respectively. A total of 131 and 121 men, respectively, completed the 12-week questionnaire.
The researchers found that at six and 12 weeks post-surgery, urinary function scores did not differ significantly between the groups (P = 0.09 and 0.48, respectively). Sexual function scores did not differ significantly between the groups at six or 12 weeks (P = 0.45 and 0.18, respectively). The proportions with positive surgical margins were not significantly different in a superiority test (10 percent in the radical retropubic prostatectomy group and 15 percent in the robot-assisted laparoscopic prostatectomy group; P = 0.21).
“Longer term follow-up is needed,” the authors write. “In the interim, we encourage patients to choose an experienced surgeon they trust and with whom they have rapport, rather than a specific surgical approach.”
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