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Sedentary Behavior Linked to Diabetic Retinopathy

60 minute/day increase in sedentary behavior increases odds of mild or worse diabetic retinopathy

FRIDAY, Aug. 5, 2016 (HealthDay News) — Sedentary behavior (SB) seems to be associated with diabetic retinopathy (DR), according to a research letter published online Aug. 4 in JAMA Ophthalmology.

Paul D. Loprinzi, Ph.D., from the University of Mississippi in University, examined the correlation between SB and DR using data from the 2005 to 2006 National Health and Nutrition Examination Survey. Data were analyzed for 282 participants with diabetes.

Loprinzi found that after adjustment for confounding variables, a 60-minute/day increase in SB correlated with an increase in the odds of having mild or worse DR (odds ratio [OR], 1.16; 95 percent confidence interval [CI], 1.00 to 1.35; P = 0.04). There was no correlation for total physical activity with DR (OR, 1.00; 95 percent CI, 0.99 to 1.01; P = 0.36). SB remained associated with DR even after adjustment for duration of diabetes (OR, 1.29; 95 percent CI, 1.04 to 1.60; P = 0.02). There was no evidence for a multiplicative effect of SB and physical activity on DR (OR, 1.00; 95 percent CI, 0.99 to 1.01; P = 0.89).

“The plausibility of this positive association between SB and DR may in part be a result of the increased cardiovascular disease risks associated with SB, which in turn may increase the risk of DR,” Loprinzi writes. “This association does not prove a cause and effect of SB and increased chance of worsening DR.”

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