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FDA Approves Imbruvica to Treat Chronic Graft Versus Host Disease

Drug sanctioned for patients with cGVHD who do not respond to other forms of therapy

Signature ID’d for Allergen-Specific Type 2 Helper Cells

Method for identifying pathogenic T cells implicated in allergic response may allow use as biomarker, target

IgG-Degrading Enzyme Allows HLA-Incompatible Transplant

IgG-degrading enzyme from Streptococcus pyogenes reduces, eliminates donor-specific antibodies

Are Clinicians Overprescribing Gabapentinoids for Pain?

Non-trivial side effects, no robust evidence for off-label use of gabapentinoids for other types of pain

Less Than Half of Stroke Discharges Prescribed a Statin

Prescribing differences by age, sex seen in 'Stroke Belt' in the southern U.S. versus rest of nation

FDA Approves Idhifa for Some With Acute Myeloid Leukemia

For adults with relapsed or refractory AML who have an IDH2 genetic mutation

Downregulation of miR-126 Augments DNA Damage Response

Reduced miR-126 levels in lungs from mice exposed to cigarette smoke, smokers' lung epithelial cells

TXNIP Blocks Autophagic Flux, Causes α-Synuclein Accumulation

Thioredoxin-interacting protein plays important role in degeneration of dopaminergic neurons

Mechanisms ID’d for Curcumin Resensitization of Cancer Cells

Compound helps turn off pathways linked to chemoresistance in pancreatic ductal adenocarcinoma

Review: Levetiracetam Best Monotherapy for Partial Seizures

First-line tx sodium valproate tops carbamazepine, topiramate for generalized onset seizures