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For patients initiating oral anticoagulant therapy

Hospitalization for Upper GI Bleed Highest With Rivaroxaban

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Upper gastrointestinal bleeding hospitalization risk lower for anticoagulant tx with PPI cotherapy
Overlapping inpatient orthopedic surgery is noninferior to nonoverlapping surgery with respect to perioperative complications

Overlapping Orthopedic Surgery Noninferior for Patient Safety

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Reduced odds of perioperative complications seen for overlapping surgery versus nonoverlapping surgery
Both restrictive and obstructive lung disease are associated with an increased risk for incident dementia and mild cognitive impairment

Restrictive, Obstructive Lung Disease Linked to Dementia Risk

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Associations seen for both Alzheimer's disease-related dementia and cerebrovascular etiologies
The labels of prescription opioid painkillers should advise doctors to consider simultaneously prescribing the opioid overdose antidote naloxone

FDA Advisory Panels: Prescribe Naloxone With Opioid Painkillers

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Federal government urged to make naloxone more widely available, easier to obtain, and cheaper
A sickle cell disease prevention and treatment program in the United States has been reauthorized to receive nearly $5 million each year over the next five years.

New Law Boosts Fight Against Sickle Cell Disease

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In 2018, the National Institutes of Health was funded approximately $115 million for research of the disease
For patients with resected pancreatic cancer

Modified-FOLFIRINOX Beneficial in Resected Pancreatic Cancer

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Disease-free, overall survival significantly longer compared with gemcitabine, but more adverse events
For sedentary adults at risk for cognitive decline

Exercise Promotes Executive Functioning in Sedentary Adults

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Significant improvements seen in executive functioning for those at risk for cognitive decline
The density of greenness near residences is associated with lower urinary levels of epinephrine and F2-isoprostane

Residential Greenness Linked to Cardiovascular Disease Risk

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More greenness near residence linked to lower urinary levels of epinephrine and F2-isoprostane
For postmenopausal women

Postmenopausal Vaginal Estrogen Not Tied to Negative Health Outcomes

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No difference in cardiovascular disease, cancer, hip fracture for users or nonusers of vaginal estrogen
First-trimester ondansetron use is associated with a small increased risk for oral cleft but no increased risk for congenital malformations or cardiac malformations

Cardiac Malformations Not Up With First-Trimester Ondansetron

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No increased risk observed for congenital malformations; small increased risk seen for oral clefts