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The clinical benefits of tofacitinib in combination with methotrexate are sustained over two years among patients with rheumatoid arthritis

Tofacitinib Benefits Sustained for Two Years in Patients With RA

Safety, tolerability through 24 months was consistent with 12-month tofacitinib analysis
High levels of physical activity correlate with prevalent coronary artery calcification but are not linked to increased mortality

High Physical Activity Levels Tied to Coronary Artery Calcification

But no increased mortality risk with high physical activity levels, CAC of ≥100 Agatston units
In patients with cirrhosis

Frailty Tied to Liver Transplant Wait-List Mortality in Cirrhosis

Cirrhosis patients with ascites or hepatic encephalopathy are more likely to experience frailty
Opioids may be overprescribed to children after orthopedic surgery for supracondylar humerus fractures

After Elbow Surgery, Children May Be Overprescribed Opioids

Patients who had supracondylar humerus fracture sx used less than 25 percent of prescribed drugs
A shortage of the anti-anxiety drug buspirone in the United States has patients and doctors concerned.

Shortage of Anxiety Drug Creates Alarm Among Patients, Doctors

Buspirone price has fallen so low that many manufacturers claim they cannot make a profit on it
Three-quarters of students aged 11 to 15 years from government schools in India receiving spectacles wear them at follow-up

Most Students Receiving Spectacles Wear Them at Follow-Up

Poorer presenting visual acuity and improvement in visual acuity with correction predict spectacle wear
Improving clinic capacity to respond to patients' social needs may reduce primary care physician burnout

Physician Burnout Tied to Ability to Address Social Needs

Risk for burnout lower in clinics with social worker, pharmacist on care team
Discontinuing tumor necrosis factor inhibitors before gestational week 20 in women with well-controlled rheumatoid arthritis or juvenile idiopathic arthritis is not associated with disease worsening in late pregnancy

Discontinuing TNFi Before Gestational Week 20 Is Feasible

No clinically meaningful disease worsening among women with well-controlled RA, juvenile arthritis
Physicians who receive direct pharmaceutical payments for opioid prescribing prescribe more opioids

Direct-to-Doctor Payments May Increase Opioid Prescribing

Prescribers receiving opioid-specific payments prescribed 8,784 more opioid daily doses per year
More black index patients diagnosed with HIV are interviewed for partner services than all index patients combined

CDC: Most Black HIV Patients Interviewed for Partner Services

78 percent of partners identified were notified of potential exposure; 47 percent were tested for HIV