Home Pathology June 2016 Briefing – Pathology

June 2016 Briefing – Pathology

Here are what the editors at HealthDay consider to be the most important developments in Pathology for June 2016. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

BRCA1 Mutations May Raise Risk of Serous/Serous-Like Uterine CA

THURSDAY, June 30, 2016 (HealthDay News) — Women with BRCA mutations undergoing risk-reducing salpingo-oophorectomy (RRSO) do not have increased risk for uterine cancer, but the risk of serous/serous-like endometrial carcinoma is increased for BRCA1+ women, according to a study published online June 30 in JAMA Oncology.

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Malaria Vaccine Protection Short-Lived in Young Children

THURSDAY, June 30, 2016 (HealthDay News) — The world’s most promising malaria vaccine (RTS,S/AS01) appears to offer only short-lived protection, and may increase children’s long-term risk of contracting malaria if they live in a region with heavy transmission of the parasite, according to a study published in the June 30 issue of the New England Journal of Medicine.

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FDA Approves New Test to Help Detect Drug-Resistant Bacteria

THURSDAY, June 30, 2016 (HealthDay News) — The Xpert Carba-R Assay diagnostic, which tests patient specimens for genetic markers associated with drug-resistant bacteria, has been approved by the U.S. Food and Drug Administration.

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Spinal Cord Transplant of Neural Stem Cells Can Be Safe in ALS

THURSDAY, June 30, 2016 (HealthDay News) — Intraspinal transplantation of human spinal cord-derived neural stem cells appears feasible for patients with amyotrophic lateral sclerosis (ALS), but it’s not yet clear whether the treatment provides any benefits, according to a study published online June 29 in Neurology.

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Zika Virus Congenital Syndrome: A New Teratogenic Disease

THURSDAY, June 30, 2016 (HealthDay News) — Zika virus congenital syndrome is a new teratogenic disease, with many definite or probable cases presenting with normal head circumference values, according to research published online June 29 in The Lancet.

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Metabolomics Signature Can Predict GDM to T2DM Transition

THURSDAY, June 30, 2016 (HealthDay News) — A metabolomics signature can predict the transition from gestational diabetes mellitus (GDM) to type 2 diabetes (T2D), according to a study published online June 23 in Diabetes.

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Florida Reports First Case of Zika-Linked Microcephaly

WEDNESDAY, June 29, 2016 (HealthDay News) — Florida’s first case of a Zika-related birth defect has been reported by state officials.

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Cardiovascular Disease Mortality Progress Slowing Down in U.S.

WEDNESDAY, June 29, 2016 (HealthDay News) — The rate of decline in cardiovascular disease mortality has decelerated, according to research published online June 29 in JAMA Cardiology.

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Too Little, Too Much Sleep Can Impair Insulin Sensitivity in Men

WEDNESDAY, June 29, 2016 (HealthDay News) — Too much or too little sleep may raise the risk of diabetes in men, but not women, according to a study published online June 29 in the Journal of Clinical Endocrinology & Metabolism.

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Prostate Cancer Diagnoses Down From 2011 to 2013

WEDNESDAY, June 29, 2016 (HealthDay News) — From 2011 to 2013 there was a decrease in prostate cancer (PC) diagnoses, especially for younger men and low-risk disease, according to a research letter published online June 23 in JAMA Oncology.

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Electronic Record Demands Are Overwhelming Many Physicians

WEDNESDAY, June 29, 2016 (HealthDay News) — Physicians using electronic practice tools report higher rates of burnout and increased frustration with the amount of computerized paperwork, according to research published online June 27 in the Mayo Clinic Proceedings.

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Genetic Heart Condition Common Cause of Sudden Death in Sports

WEDNESDAY, June 29, 2016 (HealthDay News) — About one-third of sudden deaths are caused by hypertrophic cardiomyopathy, according to research published recently in The American Journal of Medicine.

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Pregnancy May Lengthen Life of Zika Virus Infection

WEDNESDAY, June 29, 2016 (HealthDay News) — Infection with the Zika virus may protect against future infection, but pregnancy seems to extend how long the virus stays in the body, according to findings published online June 28 in Nature Communications.

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Two Vaccines Deemed Feasible Against Zika Virus Infection

TUESDAY, June 28, 2016 (HealthDay News) — Experimental studies support the effectiveness of two vaccine candidates against the Zika virus, according to research published online June 28 in Nature.

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Coenzyme Q10 Levels Linked to Multiple System Atrophy

TUESDAY, June 28, 2016 (HealthDay News) — Patients with multiple system atrophy (MSA) have reduced levels of coenzyme Q10 (CoQ10), according to a study published online June 27 in JAMA Neurology.

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Few Young Males Receive HIV Testing at Physician Office Visits

TUESDAY, June 28, 2016 (HealthDay News) — Few young males receive HIV testing during visits to physicians’ offices, although the rates are higher for black and Hispanic males than for white males, according to a report published in the June 24 issue of the U.S. Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report.

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Clopidogrel Plus Aspirin Good for Noncarriers of CYP2C19 Variants

TUESDAY, June 28, 2016 (HealthDay News) — For patients with minor ischemic stroke or transient ischemic attack, the risk of new stroke is reduced with use of clopidogrel plus aspirin versus aspirin alone among those who are not carriers of the CYP2C19 loss-of-function alleles, according to a study published online June 23 in the Journal of the American Medical Association. The research was published to coincide with the Second Annual Scientific Session of the Chinese Stroke Association and the Tiantan International Stroke Conference, held from June 24 to 26 in Beijing.

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Patients Face High Hospital Bills Despite Having Insurance

MONDAY, June 27, 2016 (HealthDay News) — Costs of hospitalization for privately insured adults rose more than 37 percent over five years, with patients paying more than $1,000 on average by 2013, according to research published online June 27 in JAMA Internal Medicine.

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CDC Expert Says Flint Water Crisis Could Easily Have Been Avoided

MONDAY, June 27, 2016 (HealthDay News) — Analysis of blood samples from young children in Flint, Mich., shows they had much more lead in their blood when the city used local drinking water in an effort to cut costs, according to research published in the early release June 24 issue of the U.S. Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report.

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Lymphoplasmacytic Infiltrate Seen in Syphilis, HIV Co-Infection

MONDAY, June 27, 2016 (HealthDay News) — Skin biopsies from patients co-infected with HIV and syphilis have moderate to extensive lymphoplasmacytic infiltrate, according to research published online June 14 in the Journal of Cutaneous Pathology.

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ALT Levels Within Normal Range Linked to Cardiovascular Events

MONDAY, June 27, 2016 (HealthDay News) — Alanine aminotransferase (ALT) levels within normal range are associated with cardiovascular event risk, according to a study published in the July 1 issue of The American Journal of Cardiology.

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Genetic Picture of Colorectal Cancer Clarified

FRIDAY, June 24, 2016 (HealthDay News) — Scientists have identified new gene mutations that may be tied to colorectal cancer (CRC). The study was published online June 22 in Nature Communications.

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DNA Tests May Aid Diagnosis of CNS Infections

FRIDAY, June 24, 2016 (HealthDay News) — Genetic testing may help diagnose or rule out central nervous system (CNS) infections, according to research published online June 13 in Neurology: Neuroimmunology & Neuroinflammation.

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2017 Will Bring Premium Rate Increases Under ACA

FRIDAY, June 24, 2016 (HealthDay News) — Health insurance premiums under the Affordable Care Act will rise in 2017, analysts and insurance brokers say.

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Novel Lipid Mediators May Play Role in Omega-3 PUFA Effects

FRIDAY, June 24, 2016 (HealthDay News) — Novel lipid mediators may be involved in the beneficial effects associated with omega-3 polyunsaturated fatty acids (PUFAs) in obesity, according to a study published online June 16 in Diabetes.

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12-Gene Recurrence Score Valid in Colon Cancer Without Chemo

FRIDAY, June 24, 2016 (HealthDay News) — The 12-gene Recurrence Score assay is valid for stage II and III colon cancer without chemotherapy, according to a study published online June 20 in the Journal of Clinical Oncology.

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K13 Polymorphism Analysis Can ID Resistance Mutations

THURSDAY, June 23, 2016 (HealthDay News) — Plasmodium falciparum gene Kelch (K13)-propeller sequence polymorphism analysis can assist with surveillance of artemisinin resistance, according to a study published in the June 23 issue of the New England Journal of Medicine.

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Exposure to the Dengue Virus May Up Potency of Zika Infection

THURSDAY, June 23, 2016 (HealthDay News) — Prior exposure to the dengue fever virus may increase the severity of Zika virus infection, according to a study published online June 23 in Nature Immunology.

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Adverse Outcomes Up With Kidney Retransplant in HIV+

THURSDAY, June 23, 2016 (HealthDay News) — Primary HIV+ kidney transplant recipients who lose their graft and seek retransplantation (re-KT) have an increased risk of death and graft loss, according to a study published online June 15 in the American Journal of Transplantation.

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Decrease in Nevus Biopsies With Total Body Photography

THURSDAY, June 23, 2016 (HealthDay News) — Total body photography (TBP) is associated with a reduction in nevus biopsies, according to a study published in the July issue of the Journal of the American Academy of Dermatology.

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Genetic Testing Helps Identify Causes of Sudden Cardiac Death

THURSDAY, June 23, 2016 (HealthDay News) — Genetic testing can increase the identification of a possible cause of sudden cardiac death in children and young adults, according to a study published in the June 23 issue of the New England Journal of Medicine.

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Early Antibiotic Treatment Can Be Beneficial in Cystic Fibrosis

THURSDAY, June 23, 2016 (HealthDay News) — For patients with cystic fibrosis (CF), early treatment of Pseudomonas aeruginosa (Pa) may be beneficial, according to a study published online June 16 in the Journal of Clinical Pharmacy and Therapeutics.

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Failure of Dual Antimicrobial Therapy for Gonorrhea Reported

THURSDAY, June 23, 2016 (HealthDay News) — In a case report published in the June 23 issue of the New England Journal of Medicine, dual antimicrobial therapy failure is described in the treatment of gonorrhea.

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Zika Infection Also Linked to Uveitis in Adults

THURSDAY, June 23, 2016 (HealthDay News) — In a letter published online June 22 in the New England Journal of Medicine, researchers describe the case of a man who was infected with Zika and developed uveitis.

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Hep C Core Antigen Assays Show High Sensitivity, Specificity

THURSDAY, June 23, 2016 (HealthDay News) — Testing for hepatitis C virus core antigen (HCVcAg) could be a good alternative for nucleic acid testing (NAT) for diagnosis of chronic HCV, according to a review and meta-analysis published online June 21 in the Annals of Internal Medicine.

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Statins Could Reduce Risk of Infection in Stroke Patients

WEDNESDAY, June 22, 2016 (HealthDay News) — Statins could significantly reduce the risk of infection in stroke patients, according to a study published online June 9 in the Journal of Stroke and Cerebrovascular Diseases.

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Dropping Troponin Test May Up Number of Donor Hearts Available

WEDNESDAY, June 22, 2016 (HealthDay News) — The troponin I blood test that’s used to check the health of a donor heart may not accurately predict if a heart transplant will be successful, according to a study published online June 21 in Circulation: Heart Failure.

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Materials in Vitreous Seen in About Half of Phaco Cases

WEDNESDAY, June 22, 2016 (HealthDay News) — Materials in the vitreous (MIV) are identified in approximately half of phacoemulsification cataract surgery (phaco) cases, in Berger’s space or the anterior vitreous (AV), according to a study published online June 17 in Clinical & Experimental Ophthalmology.

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High Glycemic Index/Load Diet Linked to Acne Vulgaris

WEDNESDAY, June 22, 2016 (HealthDay News) — Patients with acne vulgaris have significantly higher glycemic index and glycemic load levels and significantly lower serum adiponectin levels, according to a study published in the July issue of the Journal of the American Academy of Dermatology.

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25(OH)D Levels Linked to Survival in Pancreatic Cancer

WEDNESDAY, June 22, 2016 (HealthDay News) — Prediagnostic 25-hydroxyvitamin D (25[OH]D) levels are associated with survival in pancreatic cancer, according to a study published online June 20 in the Journal of Clinical Oncology.

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Exercise May Be Protective Against Epithelial Ovarian Cancer

TUESDAY, June 21, 2016 (HealthDay News) — Lack of exercise is associated with an increased risk of epithelial ovarian cancer (EOC) and mortality, two new studies suggest.

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Striatal D2 Receptors, Age Linked to Sucrose Preference

TUESDAY, June 21, 2016 (HealthDay News) — For subjects without obesity, striatal D2 receptor (D2R) binding potential and age are associated with sucrose preference, according to a study published online June 15 in Diabetes.

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Persistent High Spending Common in Year Before Death

TUESDAY, June 21, 2016 (HealthDay News) — Almost half of older Medicare beneficiaries have high persistent spending throughout the full year before death, according to a study published in the June issue of Health Affairs.

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Risk of T1DM Up in Children With Autoantibody Reversion

TUESDAY, June 21, 2016 (HealthDay News) — The risk of type 1 diabetes remains elevated for children who have developed multiple β-cell autoantibodies, even after reversion of individual autoantibodies, according to a study published online June 16 in Diabetes Care.

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Study Looks at Recurrence After Laparoscopic Radical Cystectomy

TUESDAY, June 21, 2016 (HealthDay News) — Early unexpected recurrences after laparoscopic radical cystectomy occur in 8.7 percent of patients with favorable pathological characteristics, according to a study published in the June issue of The Journal of Urology.

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Rates of Parkinson’s Disease Rising Among U.S. Males

MONDAY, June 20, 2016 (HealthDay News) — Rates of Parkinson’s disease have increased for U.S. men over the past three decades, and the trend could be tied to declines in smoking, according to a report published online June 20 in JAMA Neurology.

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AAP: No Amount of Lead Exposure Is Safe for Children

MONDAY, June 20, 2016 (HealthDay News) — No amount of lead exposure is safe for children, and stricter regulations are needed to protect youngsters from this serious health threat, according to new recommendations by the American Academy of Pediatrics (AAP), published online June 20 in Pediatrics.

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Reset Room Can Help Address Physician Burnout

MONDAY, June 20, 2016 (HealthDay News) — The creation of a reset room is one of several solutions that can help physicians and medical providers address burnout, according to a report published by the American Medical Association.

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Scientists Pinpoint Potential Drug Target for Zika Virus

MONDAY, June 20, 2016 (HealthDay News) — A potential way to prevent Zika and similar viruses from spreading in the body has been identified, according to research published online June 17 in Nature.

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PSA Cut Point of ≥0.4 ng/mL Predicts Progression

MONDAY, June 20, 2016 (HealthDay News) — A prostate-specific antigen cut point of ≥0.4 ng/mL predicts future disease progression, according to a study published in the June issue of The Journal of Urology.

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Most Women Diagnosed With HIV in Pregnancy Retained in Care

MONDAY, June 20, 2016 (HealthDay News) — Most women diagnosed with HIV during pregnancy are still retained in clinical care over the first year postpartum, according to a study published in the July issue of Obstetrics & Gynecology.

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Review IDs Gut Microbiota Changes in Irritable Bowel

FRIDAY, June 17, 2016 (HealthDay News) — Patients with irritable bowel syndrome (IBS) have alterations in their gut microbiota, with distinct alterations for Chinese patients, according to a review and meta-analysis published online June 14 in the Journal of Gastroenterology and Hepatology.

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Number of Circulating Tumor Cells Up After Surgery in SCCHN

FRIDAY, June 17, 2016 (HealthDay News) — Most patients with squamous cell carcinoma of the head and neck (SCCHN) have an increase in the number of circulating tumor cells (CTCs) after surgical resection, according to a study published online June 5 in Head & Neck.

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CDC: New Test May Help Screen Blood Donations for Zika

FRIDAY, June 17, 2016 (HealthDay News) — The Zika virus is spreading through Puerto Rico, placing hundreds of pregnant women at risk for delivering babies with microcephaly, and blood centers in Puerto Rico have begun testing donations for Zika, the U.S. Centers for Disease Control and Prevention said Friday.

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Strategy Needed to Address Impending Physician Shortage

FRIDAY, June 17, 2016 (HealthDay News) — Steps should be taken to combat the impending physician shortage of between 61,700 and 94,700 doctors that the United States is expected to face over the next decade, according to an article published in Medical Economics.

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Gross Total Resection for the Best Results in Glioblastoma

FRIDAY, June 17, 2016 (HealthDay News) — More extensive surgeries may best optimize patient survival in glioblastoma multiforme, according to research published online June 16 in JAMA Oncology.

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Obesity in Older Male Teens Ups Risk for Liver Disease Later

FRIDAY, June 17, 2016 (HealthDay News) — Older teen boys who are overweight or obese could be at increased risk for severe liver disease later in life, according to a study published online June 16 in the Journal of Hepatology.

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Experimental Antibiotic Shows Promise in Fight Against MRSA

THURSDAY, June 16, 2016 (HealthDay News) — An experimental antibiotic has shown promise against methicillin-resistant Staphylococcus aureus (MRSA) in animals, according to a study published in the July issue of Antimicrobial Agents and Chemotherapy.

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Soles of the Feet Should Also Be Checked for Skin Cancer

THURSDAY, June 16, 2016 (HealthDay News) — Stress and damage caused by walking or running could be a risk factor for melanoma on the soles of the feet, according to a research letter published in the June 16 issue of the New England Journal of Medicine.

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Zika Infection in Third Trimester May Not Harm Development

THURSDAY, June 16, 2016 (HealthDay News) — The danger of Zika-related birth defects may be confined to maternal infections that occur during the first two trimesters of pregnancy, according to a study led by Margaret Honein, Ph.D., of the U.S. Centers for Disease Control and Prevention, and published online June 15 in the New England Journal of Medicine.

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Potential Impact of Single-Payer Health Care Discussed

THURSDAY, June 16, 2016 (HealthDay News) — Democratic presidential candidate Bernie Sanders is promoting his version of single-payer health care, although the actual impact of such a system is unclear, according to a report published in Medical Economics.

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Genetic Data Help ID Risk of Future Impaired Fasting Glucose

THURSDAY, June 16, 2016 (HealthDay News) — The addition of genetic risk variant data to conventional childhood risk factors improves risk assessment of impaired fasting glucose (IFG) and type 2 diabetes in adulthood, according to a study published online June 13 in Diabetes Care.

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Prices for Care Rise Significantly As Multi-Hospital Systems Emerge

THURSDAY, June 16, 2016 (HealthDay News) — Hospital prices in California increased substantially from 2004 to 2013, with a larger increase in hospitals that are members of multi-hospital systems, according to a study published online June 9 in Inquiry.

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No Conclusive Link Between Melanoma Risk, PDE5 Inhibitors

WEDNESDAY, June 15, 2016 (HealthDay News) — The small apparent increase in risk of melanoma in men prescribed phosphodiesterase type 5 (PDE5) inhibitors may be explained by greater sun exposure, according to new research published online June 14 in PLOS Medicine.

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aHSCT Should Be Standard of Care for HIV-Related Lymphoma

WEDNESDAY, June 15, 2016 (HealthDay News) — Patients living with HIV are at high risk for lymphoma, and, according to a study published online June 13 in Blood, autologous hematopoietic stem-cell transplantation (aHSCT) should be standard treatment in these cases.

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HIV Infection Negatively Affects Bone Acquisition

WEDNESDAY, June 15, 2016 (HealthDay News) — HIV infection with T cell activation is associated with lower bone mineral density (BMD) and stiffness, according to a study published online June 10 in the Journal of Bone and Mineral Research.

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Even Short-Term T2DM Remission Reduces Risk of Microvascular Dz

TUESDAY, June 14, 2016 (HealthDay News) — For patients with type 2 diabetes, remission after bariatric surgery is associated with a reduced risk of microvascular disease, even after subsequent relapse, according to a study published online June 6 in Diabetes Care.

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Midlife PSA Levels Predict Future Lethal Prostate Cancer

TUESDAY, June 14, 2016 (HealthDay News) — Prostate-specific antigen (PSA) levels in midlife predict future lethal prostate cancer (PCa) risk, according to a study published online June 13 in the Journal of Clinical Oncology.

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Abnormal Pap Posthysterectomy for ~30 Percent of HIV+ Women

TUESDAY, June 14, 2016 (HealthDay News) — About one-in-three HIV-infected women with no prehysterectomy history of abnormal Pap results have abnormal vaginal Pap results after hysterectomy, according to a study published in the July issue of Obstetrics & Gynecology.

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Report Describes Primary Clear Cell Sarcoma of Head, Neck

MONDAY, June 13, 2016 (HealthDay News) — Three cases of primary clear cell sarcoma of the head and neck have been described in three male patients, according to a review published online June 6 in the Journal of Cutaneous Pathology.

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WHO Advises Delaying Pregnancy in Zika-Affected Areas

FRIDAY, June 10, 2016 (HealthDay News) — In order to avoid having infants with Zika-related birth defects, women living in areas where the virus is circulating should consider delaying pregnancy, according to the World Health Organization.

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New Post-Chemo Stem Cell Transplant Promising in MS

FRIDAY, June 10, 2016 (HealthDay News) — A treatment combining chemotherapy and an autologous hematopoietic stem-cell transplantation (aHSCT) could represent a major advance against aggressive multiple sclerosis (MS), according to a study published online June 9 in The Lancet.

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Elevated 3 Alpha-Diol G Levels for Many Women With Acne

FRIDAY, June 10, 2016 (HealthDay News) — About half of adult women with acne, with normal androgenic status, have elevated levels of 3 alpha-diol G, according to a study published online June 6 in the Journal of Cosmetic Dermatology.

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CYP2C8, SLCO1B1 Variants Impact Response to Rosiglitazone

FRIDAY, June 10, 2016 (HealthDay News) — Genetic variants in CYP2C8 and SLCO1B1 impact the therapeutic response to rosiglitazone in patients with type 2 diabetes, according to a study published online June 6 in Diabetes Care.

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Oral Contraceptive Use Ups Surgery Risk in Crohn’s

FRIDAY, June 10, 2016 (HealthDay News) — For females with Crohn’s disease (CD), long-term use of oral contraceptives (OCs) is associated with increased risk of surgery, according to a study published in the June issue of Gastroenterology.

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Renal Function Tests Stratify Risk in Pregnant Women With HTN

THURSDAY, June 9, 2016 (HealthDay News) — Baseline renal function tests can stratify the risk of severe preeclampsia in pregnant women with chronic hypertension, according to a study published in the July issue of Obstetrics & Gynecology.

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Temporal hs-cTnT Increase Linked to Risk of CHD, CHF

THURSDAY, June 9, 2016 (HealthDay News) — Temporal increases in high-sensitivity cardiac troponin T (hs-cTnT) are associated with increased risk of coronary heart disease (CHD), heart failure, and all-cause mortality, according to a study published online June 8 in JAMA Cardiology.

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Histopathologic Features of Tinea Identified

WEDNESDAY, June 8, 2016 (HealthDay News) — Histopathologic features of tinea have been identified, and include a compact stratum corneum, parakeratosis, mild spongiosis, and neutrophils in the stratum corneum and within the blood vessels, according to research published online June 6 in the Journal of Cutaneous Pathology.

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Fatty Acid Fractions in Breast Adipose Tissue May ID Carcinoma

WEDNESDAY, June 8, 2016 (HealthDay News) — For postmenopausal women, fatty acid fractions in breast adipose tissue may be associated with invasive ductal carcinoma, according to a study published online June 7 in Radiology.

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USPSTF Recommends Screening for Syphilis Infection

TUESDAY, June 7, 2016 (HealthDay News) — The U.S. Preventive Services Task Force (USPSTF) recommends screening for syphilis infection in non-pregnant persons who are at increased risk of infection. These findings form the basis of a recommendation statement published in the June 7 issue of the Journal of the American Medical Association.

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Review Links Tonsillectomy to Risk of Crohn’s Disease

TUESDAY, June 7, 2016 (HealthDay News) — Tonsillectomy is associated with increased risk of developing Crohn’s disease (CD), but not ulcerative colitis (UC), according to a review and meta-analysis published in the June issue of the Journal of Gastroenterology and Hepatology.

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U-Shaped Pattern for Dietary Calcium Intake, Fracture Risk

MONDAY, June 6, 2016 (HealthDay News) — Dietary calcium intake seems to have a U-shaped correlation with fracture risk in men and possibly in women, according to a study published online May 21 in the Journal of Bone and Mineral Research.

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High-Sensitivity Cardiac Troponin I Assay Shows Efficiency in ER

FRIDAY, June 3, 2016 (HealthDay News) — A high-sensitivity cardiac troponin I assay can help identify or exclude the diagnosis of myocardial infarction (MI) in the emergency department, according to two studies published online June 1 in JAMA Cardiology.

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More Evidence That Low-Dose Aspirin Ups Survival in CRC

FRIDAY, June 3, 2016 (HealthDay News) — Colorectal cancer (CRC) patients who take low-dose aspirin may have better survival odds, according to a study published online May 31 the Journal of Clinical Oncology.

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15.5 Million Americans Now Surviving Cancer

FRIDAY, June 3, 2016 (HealthDay News) — Cancer survivors in the United States reached record numbers this year — 15.5 million — and the American Cancer Society predicts they’ll total more than 20 million in another decade. The report, prepared by the American Cancer Society in collaboration with the U.S. National Cancer Institute, was published online June 2 in CA: A Cancer Journal for Clinicians.

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Twin Gestation Ups Risk of Gestational Diabetes Mellitus

FRIDAY, June 3, 2016 (HealthDay News) — Twin gestation is associated with increased risk of gestational diabetes mellitus (GDM), according to an article published online May 23 in Diabetes Care.

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Chemical Reactions Can Create Health Hazards in Pools, Hot Tubs

THURSDAY, June 2, 2016 (HealthDay News) — The disinfectants used to keep pools clean can create dangerous disinfection byproducts (DBPs) when combined with sweat, personal care products, and urine, according to research published online April 28 in Environmental Science & Technology.

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HSCT No Better Than Chemo in Philadelphia-Negative ALL

THURSDAY, June 2, 2016 (HealthDay News) — For patients ≥40 years of age with Philadelphia (Ph)-negative acute lymphoblastic leukemia (ALL), hematopoietic stem-cell transplantation (HSCT) in first remission is associated with lower cumulative incidence of relapse (CIR), but worse non-relapse mortality (NRM), compared with chemotherapy alone, according to a study published online May 6 in the American Journal of Hematology.

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Triclosan Exposure Affects Microbiome Structure, Diversity

THURSDAY, June 2, 2016 (HealthDay News) — Triclosan exposure affects the structure and diversity of the microbiome in adult zebrafish, according to research published online May 18 in PLOS ONE.

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Decline in Complex Congenital Heart Defects in Down Syndrome

THURSDAY, June 2, 2016 (HealthDay News) — For infants diagnosed with Down syndrome there has been a reduction in the risk of complex congenital heart defects, according to a study published online June 1 in Pediatrics.

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Genes May Lower Risk of Obesity in Men of West African Descent

THURSDAY, June 2, 2016 (HealthDay News) — A new study has identified genetic factors in black men with a strong West African ancestry that are associated with a lower risk of central obesity. But this apparent benefit doesn’t extend to black women, regardless of their lineage. The study findings were published online June 1 in Frontiers in Genetics.

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CVD Risk Appears to Be Increased in Women With Migraine

WEDNESDAY, June 1, 2016 (HealthDay News) — Women who suffer from migraine headaches may have a slightly increased risk of heart disease or stroke, according to a study published online May 31 in The BMJ.

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Gene Database Offers Doctors Insights Into Breast, Ovarian CA

WEDNESDAY, June 1, 2016 (HealthDay News) — A BRCA gene database can help physicians better understand their patients’ genetic risk for breast and ovarian cancer, researchers say.

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Baby With Zika-Related Microcephaly Born at N.J. Hospital

WEDNESDAY, June 1, 2016 (HealthDay News) — A woman from Honduras who apparently became infected with the Zika virus in her home country gave birth Tuesday in a New Jersey hospital to a baby girl with microcephaly, officials said.

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More Evidence That Air Pollution Raises Blood Pressure

WEDNESDAY, June 1, 2016 (HealthDay News) — There is more evidence linking air pollution with increased risk of developing hypertension, according to a review published online May 31 in Hypertension.

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Prophylactic Antibiotics Cut Risk of Anti-EGFR Skin Rash

WEDNESDAY, June 1, 2016 (HealthDay News) — For patients receiving anti-epidermal growth factor receptor (EGFR) treatment, the risk of developing skin rash is reduced for those taking prophylactic antibiotics, according to a review published online May 23 in the British Journal of Dermatology.

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Vigilance Urged for Heparin-Induced Thrombocytopenia

WEDNESDAY, June 1, 2016 (HealthDay News) — Diagnosis and management of heparin-induced thrombocytopenia (HIT) are discussed in a review published in the May 31 issue of the Journal of the American College of Cardiology.

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Gut Microbiome Tied to Metabolic Hormones in Early Pregnancy

WEDNESDAY, June 1, 2016 (HealthDay News) — In overweight and obese women, gut microbiome composition is associated with the metabolic hormonal environment at 16 weeks of gestation, according to a study published in the May issue of Diabetes.

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Blood-Brain Barrier Leaks Seen in Patients With Early Alzheimer’s

WEDNESDAY, June 1, 2016 (HealthDay News) — Patients in the early stages of Alzheimer’s disease may have more leakages in the blood-brain barrier (BBB), according to a study published online May 31 in Radiology.

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