Home Cardiology July 2015 Briefing – Cardiology

July 2015 Briefing – Cardiology

Here are what the editors at HealthDay consider to be the most important developments in Cardiology for July 2015. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Treatment Targets Not Met by Most Older Patients With Diabetes

FRIDAY, July 31, 2015 (HealthDay News) — Only one-third of American seniors with diabetes have their disease under control as defined by the American Diabetes Association (ADA) guidelines, according to research published in the July issue of the Diabetes Care.

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FDA Warns of Confusion Between Brintellix, Brilinta

FRIDAY, July 31, 2015 (HealthDay News) — Confusion between the names of the antidepressant Brintellix (vortioxetine) and the antiplatelet Brilinta (ticagrelor) has led to the wrong medication being prescribed or dispensed, the U.S. Food and Drug Administration says.

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AMA Wants Doctor Input on EHRs, Meaningful Use

FRIDAY, July 31, 2015 (HealthDay News) — The American Medical Association (AMA) is encouraging clinicians to share their perspectives on electronic heath records (EHRs) and the meaningful use program.

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U.S. Health Spending Projected to Rise 5.8 Percent By 2024

FRIDAY, July 31, 2015 (HealthDay News) — From 2014 to 2024, U.S. health spending growth is projected to increase by about 6 percent, according to a report published online July 28 in Health Affairs.

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Social Media Can Inform Patient-Doctor Dialogue About LVADs

FRIDAY, July 31, 2015 (HealthDay News) — Social media outlets represent a promising source of information relating to left ventricular assist device treatment for heart failure, but their reliability is hampered by current lack of oversight into content, according to a study published online July 28 in Circulation: Cardiovascular Quality and Outcomes.

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New Drug Effectively Lowers Levels of Triglycerides

THURSDAY, July 30, 2015 (HealthDay News) — An experimental drug, ISIS 304801, can lower triglyceride levels by as much as 71 percent, according to study results published in the July 30 issue of the New England Journal of Medicine.

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Chocolate Consumption Shows No Impact on Risk of A-Fib

THURSDAY, July 30, 2015 (HealthDay News) — Among U.S. male physicians, chocolate consumption is not associated with risk of incident atrial fibrillation (AF), according to a study published in the Aug. 15 issue of The American Journal of Cardiology.

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LVEF Improvement for Many With Primary Prevention ICDs

THURSDAY, July 30, 2015 (HealthDay News) — Forty percent of patients with primary prevention implantable cardioverter-defibrillators (ICDs) experience improvement in left ventricular ejection fraction (LVEF), according to a study published in the Aug. 4 issue of the Journal of the American College of Cardiology.

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RAPID Score Validated for Prognosis of Pleural Infections

WEDNESDAY, July 29, 2015 (HealthDay News) — The recently developed RAPID score, which identifies the risk of mortality in patients with pleural infections based on five clinical factors, has been validated in a diverse patient cohort. The findings have been published online July 20 in the Annals of the American Thoracic Society.

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Early Invasive Strategy No Benefit 10 Years After NSTE-ACS

WEDNESDAY, July 29, 2015 (HealthDay News) — For patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS), routine early invasive strategy (coronary arteriography and myocardial revascularization, as clinically indicated) is not associated with improved outcomes at 10 years over a selective invasive strategy (coronary arteriography for recurrent ischemia only). The findings were published in the Aug. 4 issue of the Journal of the American College of Cardiology.

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2015 MOC Program Expected to Cost $5.7 Billion Over 10 Years

WEDNESDAY, July 29, 2015 (HealthDay News) — The 2015 version of the American Board of Internal Medicine (ABIM) maintenance-of-certification (MOC) program is expected to generate considerable costs, mainly due to physician time costs, according to research published online July 28 in the Annals of Internal Medicine.

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Routine Dyspnea Severity Assessment Could Aid Care

WEDNESDAY, July 29, 2015 (HealthDay News) — The majority of hospitalists believe that routinely assessing dyspnea severity would enhance their clinical decision making and positively affect patient care, according to a study published online July 20 in the Journal of Hospital Medicine.

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Patients Report Improved Care Access, Better Health With ACA

TUESDAY, July 28, 2015 (HealthDay News) — Millions more Americans have affordable health insurance, access to a personal doctor, and feel they are in better health following the first two open-enrollment periods of the Affordable Care Act (ACA), a new analysis shows. The results are published in the July 28 issue of the Journal of the American Medical Association.

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Visit-to-Visit BP Variability May Impact Cardiovascular Outcomes

TUESDAY, July 28, 2015 (HealthDay News) — Wide blood pressure fluctuations may signal an increased risk of coronary heart disease and early death, according to research published online July 28 in the Annals of Internal Medicine.

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Components of Mediterranean Lifestyle Cut Postprandial Lipemia

TUESDAY, July 28, 2015 (HealthDay News) — Components of the Mediterranean lifestyle may reduce postprandial lipemia (PPL), an independent risk factor for cardiovascular disease, according to a review published online July 7 in the American Journal of Physiology: Endocrinology and Metabolism.

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Atorvastatin/Ezetimibe Beats Atorvastatin After PCI

TUESDAY, July 28, 2015 (HealthDay News) — For Japanese patients who have undergone percutaneous coronary intervention (PCI), atorvastatin plus ezetimibe is associated with improved outcomes versus atorvastatin alone, according to a study published in the Aug. 4 issue of the Journal of the American College of Cardiology.

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FDA Approves Praluent for Certain Cases of High Cholesterol

MONDAY, July 27, 2015 (HealthDay News) — Praluent (alirocumab) injection has been approved by the U.S. Food and Drug Administration for use in addition to diet and maximally tolerated statin therapy in adults with heterozygous familial hypercholesterolemia or clinical atherosclerotic cardiovascular disease, who need additional low-density lipoprotein (LDL) cholesterol reduction.

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Delays Noted in the Reporting of Serious Patient Harms to FDA

MONDAY, July 27, 2015 (HealthDay News) — About 10 percent of cases where a drug does serious harm are not reported to the U.S. Food and Drug Administration within the required 15-day period, according to a new analysis published online July 27 as a research letter in JAMA Internal Medicine.

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Beetroot Juice Supplementation May Help Lengthen Workouts

MONDAY, July 27, 2015 (HealthDay News) — Chronic supplementation with beetroot juice (BRJ), containing nitrate, has beneficial effects on the work of the heart in response to exercise, according to a study published online June 17 in the American Journal of Physiology: Regulatory, Integrative and Comparative Physiology.

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Expansion of High-Deductible Plans to Impact Physician Care

FRIDAY, July 24, 2015 (HealthDay News) — As a result of the increasing popularity of high-deductible health care plans, patients now have more financial responsibility for medical services, which is impacting physician practices, according to an article published in Medical Economics.

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Adherence to Stroke Guidelines Overestimated by Hospitals

THURSDAY, July 23, 2015 (HealthDay News) — Many U.S. hospitals overestimate their ability to provide fast delivery of tissue plasminogen activator (tPA) to stroke patients, according to a study published online July 22 in the Journal of the American Heart Association.

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Evidence of Cellular Damage From Computed Tomography

THURSDAY, July 23, 2015 (HealthDay News) — Cellular damage occurs when people undergo computed tomography (CT) scans, but whether or not this causes cancer or any other health problems is unclear, according to a study published online July 22 in the JACC: Cardiovascular Imaging.

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Minimally-Invasive AAA Repair May Up Survival in Short Term

THURSDAY, July 23, 2015 (HealthDay News) — Minimally-invasive surgery to repair an abdominal aortic aneurysm appears to boost survival in the short term more than traditional surgery does, but that advantage diminishes over time, researchers report in the July 23 issue of the New England Journal of Medicine.

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Sleep Apnea Tied to Increased Risk of Panic Disorder

THURSDAY, July 23, 2015 (HealthDay News) — Sleep apnea seems to be associated with increased risk of subsequent panic disorder, according to a study published in the July/August issue of the Annals of Family Medicine.

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Lidocaine Patches Don’t Cut Pain After Robotic Cardiac Valve Sx

WEDNESDAY, July 22, 2015 (HealthDay News) — For patients undergoing robotic cardiac valve surgery, lidocaine 5 percent patches do not reduce acute or persistent pain, according to a study published online July 14 in Pain Medicine.

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Short Sleep Duration Ups Odds of Metabolic Syndrome

WEDNESDAY, July 22, 2015 (HealthDay News) — Short sleep duration (less than seven hours) is associated with increased likelihood of metabolic syndrome, according to a meta-analysis published online July 13 in the Annals of the American Thoracic Society.

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~40 Percent Undergo Stress Testing After PCI in VA System

WEDNESDAY, July 22, 2015 (HealthDay News) — In the Veterans Affairs (VA) health care system, nearly 40 percent of patients undergo stress testing in the two years following percutaneous coronary intervention (PCI), according to a study published online July 21 in Circulation: Cardiovascular Quality and Outcomes.

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Antibiotic May Reduce Anticoagulant Effect of Warfarin

WEDNESDAY, July 22, 2015 (HealthDay News) — The antibiotic dicloxacillin may lessen the effects of vitamin K antagonists, according to research published in the July 21 issue of the Journal of the American Medical Association.

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Bystander CPR Tied to Boosts in Survival Rates

WEDNESDAY, July 22, 2015 (HealthDay News) — Many lives could be saved if more people performed cardiopulmonary resuscitation (CPR) immediately after seeing someone go into cardiac arrest, a new study contends. The report was published in the July 21 issue of the Journal of the American Medical Association.

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Race May Factor Into Higher Risk of Sudden Cardiac Arrest

TUESDAY, July 21, 2015 (HealthDay News) — Blacks are more likely than whites to experience sudden cardiac arrest and it often occurs at an earlier age in blacks than in whites, according to research published online July 20 in Circulation.

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CDC: Aspirin Use Common Among Americans With Heart Disease

TUESDAY, July 21, 2015 (HealthDay News) — About seven in 10 Americans with a history of cardiovascular disease (CVD) or stroke regularly take aspirin, according to a report published in the July 17 issue of the U.S. Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report.

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Six-Minute Walk Test Predictive for Pulmonary Hypertension

TUESDAY, July 21, 2015 (HealthDay News) — The six-minute walk (6MW) stress echocardiography test is prognostic for development of pulmonary hypertension (PH) in connective tissue disease (CTD), according to a study published in the July 28 issue of the Journal of the American College of Cardiology.

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Intervention Can Improve Appropriateness of Telemetry Use

MONDAY, July 20, 2015 (HealthDay News) — A hospitalist-driven intervention to improve appropriate use of telemetry can reduce length of stay and costs, according to a study published online July 7 in the Journal of Hospital Medicine.

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Most Obese Patients Never Reach a Healthy Weight

FRIDAY, July 17, 2015 (HealthDay News) — Weight loss is considered a major health goal for people who are obese, but the reality is that few reach a normal weight or keep any lost pounds off, according to a study published online July 16 in the American Journal of Public Health.

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Clinicians May Harbor Biases About Sexual Orientation

FRIDAY, July 17, 2015 (HealthDay News) — Clinicians may be biased when it comes to the sexual orientation of patients, new research suggests. The study was published online July 16 in the American Journal of Public Health.

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CVD Risk Similar for Metformin + Insulin or Sulfonylureas

FRIDAY, July 17, 2015 (HealthDay News) — For patients with type 2 diabetes, the risk of myocardial infarction (MI) or stroke is similar for treatment with insulin or sulfonylureas in combination with metformin, according to a study published online July 14 in Diabetes, Obesity and Metabolism.

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Channel Length Key in Percutaneous Thrombin Injection

FRIDAY, July 17, 2015 (HealthDay News) — About 15 percent of patients with post-catheterization femoral pseudoaneurysm who undergo sonographic-guided percutaneous thrombin injection have complications, mainly arterial microembolization, according to a study published online July 14 in the Journal of Clinical Ultrasound.

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Increasing Aerobic Exercise Rx Benefits Older Women

FRIDAY, July 17, 2015 (HealthDay News) — Doubling the recommended weekly exercise amount may help postmenopausal women lose significantly more body fat, according to research findings reported online July 16 in JAMA Oncology.

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CDC: ACA May Have Boosted Uptake of Preventive Care

FRIDAY, July 17, 2015 (HealthDay News) — Americans are up to three times more likely to receive preventive care if they have health insurance, federal officials reported Thursday. And people paying for private insurance received the same preventive care as people on Medicaid or Medicare, according to the findings published in the July 17 issue of the U.S. Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report.

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Carotid Fluoro-2-Doxyglucose Uptake Predicts CV Events

FRIDAY, July 17, 2015 (HealthDay News) — For asymptomatic adults, carotid fluoro-2-deoxyglucose (FDG) uptake is a predictor of cardio-cerebrovascular events, according to a study published online July 15 in JACC: Cardiovascular Imaging.

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AMA Suggests Ways to Encourage Use of Patient Portals

THURSDAY, July 16, 2015 (HealthDay News) — Measures can be taken to encourage patients to use patient portals to help ensure practices meet current Stage 2 meaningful use requirements, according to an article published by the American Medical Association (AMA).

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Wildfires Can Trigger Acute Coronary Events for Miles Around

THURSDAY, July 16, 2015 (HealthDay News) — Wildfires create air pollution that fuels the risk for cardiovascular events, especially in older adults, researchers report in the July issue of the Journal of the American Heart Association.

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Failed Communication Associated With Readmission

THURSDAY, July 16, 2015 (HealthDay News) — Failed communication attempts are associated with readmission among Medicare beneficiaries with congestive heart failure, although the correlation is no longer significant after adjustment for other variables, according to a study published online June 26 in the Journal of the American Geriatrics Society.

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Choosing Wisely: How to Implement in Clinical Practice

THURSDAY, July 16, 2015 (HealthDay News) — Strategies should be adopted to help with implementation of the Choosing Wisely program, which was designed to address the problem of medical overuse, according to an article published in the July/August issue of Family Practice Management.

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Coronary Artery Calcium Score Has Long-Term Prognostic Utility

THURSDAY, July 16, 2015 (HealthDay News) — A zero coronary artery calcium (CAC) score has long-term prognostic utility, with CAC presence an independent predictor of mortality, according to a study published online July 15 in JACC: Cardiovascular Imaging.

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New Guidelines Deemed Better for Identifying Statin Candidates

WEDNESDAY, July 15, 2015 (HealthDay News) — Updated guidelines for cholesterol management were released in 2013 by the American College of Cardiology (ACC) and the American Heart Association (AHA). Now, a new report indicates they are more accurate and efficient than earlier guidelines in identifying adults at high risk for cardiovascular events who could benefit from statins. The findings are published in the July 14 issue of the Journal of the American Medical Association.

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Progress in Reporting Conflict of Interest Among IRB Members

TUESDAY, July 14, 2015 (HealthDay News) — Among institutional review board (IRB) members, there has been positive progress in the reporting and management of conflicts of interest, according to a study published online July 13 in JAMA Internal Medicine.

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Arts Observation Curriculum May Be Beneficial for Medical Students

TUESDAY, July 14, 2015 (HealthDay News) — Use of an arts observation curriculum can help students learn to observe objectively and articulate their observations, which are important traits for clinical practice, according to an article published online July 3 in Academic Medicine.

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Coronary Artery Disease Ups Risk of Bowel Bleeds With NSAIDs

MONDAY, July 13, 2015 (HealthDay News) — Patients with coronary artery disease are at higher risk of small bowel bleeding (SBB) when taking nonsteroidal anti-inflammatory drugs (NSAIDs), according to research published online July 6 in the Journal of Digestive Diseases.

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Secondhand Smoke Exposure Tied to Increased Stroke Risk

MONDAY, July 13, 2015 (HealthDay News) — Stroke risk is increased with secondhand smoke (SHS) exposure, according to a study published online June 23 in the American Journal of Preventive Medicine.

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Strategies Needed to Combat Weight Gain in Smoking Cessation

MONDAY, July 13, 2015 (HealthDay News) — Quitting smoking is associated with weight gain, according to a meta-analysis published online June 26 in Obesity Reviews, and clinicians are encouraged to help patients who are undergoing cessation achieve/maintain a healthy weight.

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Weekend Discharge Not Linked to Increased Readmission

FRIDAY, July 10, 2015 (HealthDay News) — For patients with acute myocardial infarction (AMI), congestive heart failure (CHF), and pneumonia, weekend discharge is not associated with 30-day readmission, according to a study published online June 30 in the Journal of Hospital Medicine.

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Many Overweight Teens Don’t See Their Weight As a Problem

FRIDAY, July 10, 2015 (HealthDay News) — Many overweight and obese teens don’t believe they have a weight problem, according to a study published online July 9 in the International Journal of Obesity.

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Uric Acid Therapy Improves Stroke Outcomes in Women

FRIDAY, July 10, 2015 (HealthDay News) — Uric acid (UA) therapy, administered in combination with thrombolysis, is more effective in cutting stroke-related disability in women than in men, according to a study published online July 9 in Stroke.

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ECG Metrics May Predict Cardiac Deaths in CKD Patients

FRIDAY, July 10, 2015 (HealthDay News) — Certain electrocardiographic (ECG) measures may improve prediction of cardiovascular death in patients with chronic kidney disease (CKD), according to research published online July 9 in the Journal of the American Society of Nephrology.

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CDC: Too Few Americans Eating Enough Fruits, Vegetables

FRIDAY, July 10, 2015 (HealthDay News) — Most Americans are not consuming the recommended amount of fruits and vegetables, according to a new report published in the July 10 issue of the U.S. Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report.

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FDA Strengthens Heart Attack, Stroke Warning for NSAIDs

FRIDAY, July 10, 2015 (HealthDay News) — The U.S Food and Drug Administration on Thursday strengthened the warning labels for non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs), regarding increased risk of heart attack or stroke.

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Breastfeeding May Help Reduce Midlife Atherosclerosis

THURSDAY, July 9, 2015 (HealthDay News) — Young women who breastfeed may have a reduced risk of early subclinical atherosclerosis during midlife, compared with those who bottle feed their babies, according to research published in the August issue of Obstetrics & Gynecology.

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Specific Biomarkers ID Cardiac Dysfunction, Mortality Risk in HIV

THURSDAY, July 9, 2015 (HealthDay News) — Specific biomarkers correlate with cardiovascular dysfunction and all-cause mortality among HIV-infected individuals, according to a study published online July 8 in JACC: Heart Failure.

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Low FEV1 in Early Adulthood May Be Important in COPD Genesis

THURSDAY, July 9, 2015 (HealthDay News) — Low forced expiratory volume in one second (FEV1) in early adulthood without accelerated decline in FEV1 correlates with later chronic obstructive pulmonary disease (COPD), according to a study published in the July 9 issue of the New England Journal of Medicine.

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FDA Approves Entresto for Heart Failure

WEDNESDAY, July 8, 2015 (HealthDay News) — The U.S. Food and Drug Administration on Tuesday approved the drug Entresto (sacubitril/valsartan) to treat heart failure.

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Non-AIDS In-Hospital Deaths Up in HIV-Infected Patients

WEDNESDAY, July 8, 2015 (HealthDay News) — Trends in hospital deaths among HIV-infected patients show that mortality during the antiretroviral therapy (ART) era is often caused by diseases and conditions other than AIDS. The findings were published online June 30 in the Journal of Hospital Medicine.

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Misunderstanding of Term ‘Hypertension’ May Impact Care

WEDNESDAY, July 8, 2015 (HealthDay News) — Misunderstanding of the term hypertension may impact antihypertensive medication use and adherence, according to a perspective piece published online July 7 in Circulation: Cardiovascular Quality and Outcomes.

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Risk of CVD Up in Newly Diagnosed Psoriatic Arthritis

TUESDAY, July 7, 2015 (HealthDay News) — Many newly diagnosed psoriatic arthritis (PsA) patients have an increased risk of future cardiovascular disease (CVD), according to a study published in the July issue of Arthritis Care and Research.

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Life Expectancy Substantially Drops With Disease Combo

TUESDAY, July 7, 2015 (HealthDay News) — While having one major health problem — such as diabetes, myocardial infarction, or stroke — can increase the risk for an early death, new research warns that the risk of dying prematurely goes up significantly for individuals with more than one of these conditions. The findings were reported in the July 7 issue of the Journal of the American Medical Association.

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Increasing Health Care Burden for Pediatric Pulmonary HTN

TUESDAY, July 7, 2015 (HealthDay News) — There is an increasing health care burden associated with morbidity and mortality of pediatric pulmonary hypertension (PH), according to a study published online July 6 in Pediatrics.

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Coronary Artery Calcification Predicts 15-Year Mortality

TUESDAY, July 7, 2015 (HealthDay News) — For patients without symptoms of coronary artery disease, the extent of coronary artery calcification (CAC) predicts 15-year mortality, according to research published in the July 7 issue of the Annals of Internal Medicine.

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Court Upholds Medical Liability Damages Cap

TUESDAY, July 7, 2015 (HealthDay News) — The non-economic damages cap under the Medical Injury Compensation Reform Act (MICRA) has been upheld again in a California court of appeal, according to a report published by the American Medical Association.

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Despite Risk to Patients, Health Providers Often Work While Sick

MONDAY, July 6, 2015 (HealthDay News) — Many health care professionals work when they are sick, putting their patients at risk for serious illness or even death, according to a study published online July 6 in JAMA Pediatrics.

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Lifestyle Factors Can Halve Heart Failure Risk in Elderly

MONDAY, July 6, 2015 (HealthDay News) — The fittest seniors are half as likely as others to suffer from heart failure, according to research published in the July 1 issue of JACC: Heart Failure.

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Health Insurance Expansion Likely to Increase HTN Treatment

MONDAY, July 6, 2015 (HealthDay News) — Efforts to expand health insurance coverage are expected to lead to increased treatment rates among nonelderly patients with hypertension, which will have significant health benefits, according to a study published online July 2 in the U.S. Centers for Disease Control and Prevention’s Preventing Chronic Disease.

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Adapted Diabetes Prevention Program Deemed Effective

MONDAY, July 6, 2015 (HealthDay News) — An adapted Diabetes Prevention Program (DPP) lifestyle intervention significantly improves cardiovascular disease-related risk factors among participants, according to a study published in the June issue of the Journal of the American Geriatrics Society.

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Asian-Language Smoking Quitline Successful Nationwide

THURSDAY, July 2, 2015 (HealthDay News) — An Asian-Language Smokers Quitline (ASQ) reaches Chinese, Korean, and Vietnamese speakers nationwide, and most callers receive medication and counseling, according to a study published online June 25 in the U.S. Centers for Disease Control and Prevention’s Preventing Chronic Disease.

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Impact of Statins on Aggression Varies by Sex

THURSDAY, July 2, 2015 (HealthDay News) — Statin use is associated with decreased aggression in men and increased aggression in women, according to a study published online July 1 in PLOS ONE.

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CVD Risk Factor Levels Too High, Even in Best-Performing States

THURSDAY, July 2, 2015 (HealthDay News) — About half of cardiovascular deaths could be prevented in U.S. adults if five major modifiable cardiovascular risk factors were eliminated, according to a study published online June 30 in the Annals of Internal Medicine.

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Sex Differences in CHD Event Risk Vary by Race

THURSDAY, July 2, 2015 (HealthDay News) — Whites have larger sex differences in the risk of incident coronary heart disease (CHD) events than blacks, according to a study published online July 1 in the Journal of the American Heart Association.

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IOM: Make CPR Mandatory High School Requirement

WEDNESDAY, July 1, 2015 (HealthDay News) — Far too few Americans are surviving cardiac arrest, and a new report issued Tuesday by the Institute of Medicine (IOM) offers strategies to boost survival rates.

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Residents’ Knowledge of High-Value Care Varies

WEDNESDAY, July 1, 2015 (HealthDay News) — U.S. internal medicine (IM) residents report varying knowledge and practice of high-value care (HVC), according to research published online June 16 in Academic Medicine.

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Race and Sex Impact Treatment in Newly Diagnosed A-Fib

WEDNESDAY, July 1, 2015 (HealthDay News) — For patients newly diagnosed with atrial fibrillation (AF), race and sex may affect treatment, according to a study published in the July issue of Heart Rhythm.

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Public Opinion Sought on New Licensure for Assistant Physicians

WEDNESDAY, July 1, 2015 (HealthDay News) — New classification of licensure for assistant physicians has been created, and public opinion is being sought by the Missouri State Board of Registration for the Healing Arts prior to filing these rules with the Secretary of State’s Office and the Joint Committee on Administrative Rules.

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In Elderly, Moderate Exercise Ups Cholesterol Transfer to HDL

WEDNESDAY, July 1, 2015 (HealthDay News) — Older women who exercise regularly have higher transfers of unesterified cholesterol (UC) and esterified cholesterol (EC) to high-density lipoprotein cholesterol (HDL-C), compared with sedentary women, according to a letter to the editor published in the June issue of the Journal of the American Geriatrics Society.

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