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Flavonol Intake May Contribute to Weight Maintenance

Increased consumption of most flavonoid subclasses inversely linked to weight change over time

THURSDAY, Jan. 28, 2016 (HealthDay News) — Increased consumption of most flavonoid subclasses is inversely associated with weight change over time, according to a study published online Jan. 28 in The BMJ.

Monica L. Bertoia, M.P.H., Ph.D., from the Harvard T.H. Chan School of Public Health in Boston, and colleagues examined whether dietary intake of specific flavonoid subclasses correlates with weight change over multiple four year intervals between 1986 and 2011. Data were included for 124,086 men and women participating in the Health Professionals Follow-up Study, Nurses’ Health Study, and Nurses’ Health Study II.

The researchers found that after adjustment for simultaneous changes in other lifestyle factors, including other aspects of diet, smoking status, and physical activity, there was an inverse correlation for increased consumption of most flavonoid subclasses, including flavonols, flavan-3-ols, anthocyanins, and flavonoid polymers, with weight change. The greatest magnitude of association was seen for anthocyanins (−0.23 lbs per additional standard deviation [SD]/day, 10 mg), flavonoid polymers (−0.18 lbs per additional SD/day, 138 mg), and flavonols (−0.16 lbs per additional SD/day, 7 mg) in pooled results. Associations remained significant for anthocyanins, proanthocyanidins, and total flavonoid polymers, but were attenuated after additional adjustment for fiber intake.

“Higher intake of foods rich in flavonols, flavan-3-ols, anthocyanins, and flavonoid polymers may contribute to weight maintenance in adulthood and may help to refine dietary recommendations for the prevention of obesity and its potential consequences,” the authors write.

Two authors disclosed financial ties to the U.S. Highbush Blueberry Council.

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