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Patients with chronic obstructive pulmonary disease with an eosinophilic phenotype may benefit from mepolizumab

Mepolizumab Beneficial in COPD With Eosinophilic Phenotype

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Lower annual rate of moderate, severe exacerbations for patients receiving 100 mg mepolizumab
Does being a physician carry a moral obligation to respond to calls for medical assistance on airplanes? That is the topic of an article published in the Sept. 12 issue of the Journal of the American Medical Association.

Are Physicians Obligated to Help on Planes?

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One administrative physician explains his sense of obligation to help
Rupture of the distal biceps tendon in a patient with heart failure with preserved ejection fraction should raise suspicion for wild-type transthyretin amyloidosis

Distal Bicep Tendon Rip Tied to Transthyretin Amyloidosis

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Findings in patients with heart failure with preserved ejection fraction
For university students with insomnia

Online Therapy for Insomnia Linked to Improved Mental Health

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University students undergoing online CBT program had reductions in insomnia, paranoia, hallucinations
For patients with locally advanced

Longer Progression-Free Survival for Durvalumab in NSCLC

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Longer median progression-free survival from randomization, higher response rate with durvalumab
Complete blood cell count parameters at commonly used or optimal thresholds do not offer high accuracy in identifying invasive bacterial infections in febrile infants (≤60 days of age)

‘Modest at Best’ Discriminatory Ability for CBC Test in Infants

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Findings among febrile infants (≤60 days) with invasive bacterial infections
The median cost of cancer drug development is $648.0 million

Median Cost of Cancer Drug Development $648.0 Million

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Total revenue from sales of 10 drugs was $67.0 billion, with total R&D spending of $7.2 billion
For patients with moderate or severe obstructive sleep apnea

AAO-HNS: Improvement in OSA With Cranial Nerve Stimulation

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Decrease in apnea-hypopnea index, and improvement in oxygen saturation, sleepiness, quality of life

Center Surgical Volume Linked to LVAD Patient Outcomes

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Worse survival at centers performing ≤10 left ventricular assist device implants/year
Airway mucin concentrations may be a marker for chronic bronchitis

Airway Mucin Concentrations May Help Predict Chronic Bronchitis

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Mean total mucin concentrations up in smokers with severe COPD, those with respiratory exacerbations