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Pathology

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For American-Indians with type 2 diabetes

Advanced Glycation End Products Tied to Renal Function Loss

AGEs improve RFL prediction in American-Indians with type 2 diabetes
Compositionally distinct human neonatal gut microbiota appear differentially related to risk of childhood atopy and asthma

Newborn Gut Microbiome May Predict Later Allergy, Asthma

Gut microbiome dysbiosis might promote CD4+ T cell dysfunction
Fatal anaphylaxis cases have been reported with administration of intravenous iron products

Reports of Fatal Anaphylaxis With IV Iron Products

Seventy-nine cases of anaphylactic reactions linked to ferumoxytol, of which 18 were fatal
From 1993 to 2010 there was an increase in the diagnosis of sleep apnea in U.S. ambulatory practice visits

Sleep Apnea Diagnoses Up Among Outpatients From 1993 to 2010

Majority of diagnoses reported by primary care providers, pulmonologists, and otolaryngologists
Long-term exposure to air pollution is associated with insulin resistance among the general population

Long-Term Exposure to Air Pollution Ups Insulin Resistance

Effect estimates much larger and highly significant for individuals with prediabetes
A one-week high glycemic index diet increases hepatic fat and glycogen stores in healthy adults compared with a low glycemic index diet

High Glycemic Index Diet Raises Hepatic Fat, Glycogen Stores

One-week high GI diet increases hepatic fat and glycogen stores compared with low GI diet
Pevonedistat

Experimental Drug Shows Promise in Melanoma

Pevonedistat was effective for inhibiting proliferation of melanoma cell lines in vitro
Fewer Americans are dying from chronic obstructive pulmonary disease

CDC: COPD-Related Mortality Mostly Down in the United States

However, rates are up for black women and middle-aged patients
Prostate-specific antigen failure is associated with increased risk of all-cause mortality for men with intermediate- or high-risk prostate cancer with no or minimal comorbidity

PSA Failure Predicts Death in Men With No, Minimal Comorbidity

Findings among men with localized intermediate- and high-risk prostate cancer
Obesity may increase survival for patients with metastatic renal cell carcinoma

Obesity May Up Survival in Metastatic Renal Cell Carcinoma

Obese/overweight patients survived 25.6 months, compared to 17.1 months for normal-weight patients