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Pathology

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For patients with early-stage colorectal cancer

Metabolic Syndrome and Obesity Up Risk of Mortality in CRC

Obese patients with metabolic syndrome have increased risk of all-cause, CRC-related death
There is a U-shaped correlation between fish consumption and all-cause mortality

U-Shaped Link for Fish Consumption, Mortality

Women only have increased mortality risk at the highest level of fish consumption
For children with gastrointestinal symptoms seen in primary care

Positive FCal Not Likely to Indicate IBD in Peds Primary Care

Negative FCal result likely to be a true negative; high sensitivity in children referred to specialist care
For American-Indians with type 2 diabetes

Advanced Glycation End Products Tied to Renal Function Loss

AGEs improve RFL prediction in American-Indians with type 2 diabetes
Compositionally distinct human neonatal gut microbiota appear differentially related to risk of childhood atopy and asthma

Newborn Gut Microbiome May Predict Later Allergy, Asthma

Gut microbiome dysbiosis might promote CD4+ T cell dysfunction
Fatal anaphylaxis cases have been reported with administration of intravenous iron products

Reports of Fatal Anaphylaxis With IV Iron Products

Seventy-nine cases of anaphylactic reactions linked to ferumoxytol, of which 18 were fatal
From 1993 to 2010 there was an increase in the diagnosis of sleep apnea in U.S. ambulatory practice visits

Sleep Apnea Diagnoses Up Among Outpatients From 1993 to 2010

Majority of diagnoses reported by primary care providers, pulmonologists, and otolaryngologists
Long-term exposure to air pollution is associated with insulin resistance among the general population

Long-Term Exposure to Air Pollution Ups Insulin Resistance

Effect estimates much larger and highly significant for individuals with prediabetes
A one-week high glycemic index diet increases hepatic fat and glycogen stores in healthy adults compared with a low glycemic index diet

High Glycemic Index Diet Raises Hepatic Fat, Glycogen Stores

One-week high GI diet increases hepatic fat and glycogen stores compared with low GI diet
Pevonedistat

Experimental Drug Shows Promise in Melanoma

Pevonedistat was effective for inhibiting proliferation of melanoma cell lines in vitro