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Zika virus infection is associated with increased incidence of neurological syndromes

Diverse Spectrum of Neurologic Syndromes Seen With Zika

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Increase in admissions for Guillain-Barré syndrome, encephalitis compared with before outbreak
Fecal calprotectin adds most to discrimination between pediatric patients with and without inflammatory bowel disease

Fecal Calprotectin Is Best Marker for Discriminating Pediatric IBD

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Blood markers, fecal calprotectin aid discrimination between pediatric patients with, without IBD
Many studies used to support U.S. Food and Drug Administration approval of high-risk medical device modifications are not controlled; and efficacy of drugs granted accelerated approval is often confirmed three years after approval

Studies Used for FDA Approval of Device Changes Often Low Quality

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And, efficacy of drugs granted accelerated approval often confirmed only years after approval
For rodents with diabetes

Hyperglycemia May Cause Caries but Not Periodontal Disease

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Findings in rodent models of type 1 and type 2 diabetes
Heterozygous HTRA1 mutations may play a role in familial cerebral small vessel disease

HTRA1 Mutations Tied to Cerebral Small Vessel Disease

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Correlation seen between mutations and MRI brain findings
There is a non-linear association between caloric load and reward

Taste, Calories Affect Metabolic Response to Sugared Beverages

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Metabolic responses up for lower calorie beverages, and when sweetness is proportional to caloric load
For humans and mice

Disruption of NAD Synthesis Tied to Congenital Malformations

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Patients with congenital mutations have lower levels of circulating nicotinamide adenine dinucleotide
A biomarker-based model provides a new tool for the prediction of cardiovascular death in patients with stable coronary heart disease

New Model Predicts Mortality in Stable Coronary Heart Disease

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Model uses age, biomarkers, clinical variables to predict cardiovascular death
Sleep-disordered breathing is associated with cognitive deficits

Sleep-Disordered Breathing Linked to Cognitive Dysfunction

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Hypoxemia and sleepiness associated with cognitive deficits, with strongest effect in APOE-ε4 carriers
Diabetes in infancy has different characteristics depending on mutation subtype

Characteristics of Diabetes in Infancy Explored

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Overall frequency of diabetic ketoacidosis 66.2 percent; odds increase with age at diagnosis