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Caffeine consumption appears to have a dose-dependent protective effect against mortality in chronic kidney disease patients

ASN: Caffeine Associated With Reduced Mortality in CKD

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Chronic kidney disease patients in highest quartile of caffeine consumption have lowest risk for mortality
The central effects of glucagon-like peptide-1 may mediate the effects of Roux-en-Y gastric bypass on central nervous system activation in response to visual and gustatory food cues

GLP-1 May Mediate Effects of Gastric Bypass on CNS Activation

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After Roux-en-Y, CNS activation reduced in response to food cues, GLP-1 levels significantly elevated
Not all prescription drug users report receiving warnings about driving impairment

Driving Impairment Warnings Often Not Given With Rx Meds

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For most drug categories, those who do receive warnings perceive higher risk of impaired driving
Systemic inflammation in midlife is associated with future neurodegeneration and cognitive aging

Midlife Systemic Inflammation Tied to Late-Life Brain Volume

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Smaller hippocampal, Alzheimer's signature region volumes seen 24 years after inflammation noted
PARP inhibitors demonstrate activity in triple-negative breast cancer tumors without BRCA1/2 mutations

PARP Inhibitors Promising Beyond BRCA1/2 Altered Tumors

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Talazoparib caused regression in 5 patient-derived xenografts, 4 without germline BRCA1/2 mutations
Black men have increased prevalence and frequency of multiple intracranial atherosclerotic plaques

Race a Factor in Intracranial Atherosclerotic Disease

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Prevalence and frequency of multiple plaques were higher for black men
Specific inflammatory biomarkers may impact the risk of developing schizophrenia

Inflammatory Biomarkers May Impact Risk of Schizophrenia

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Protective effect noted for C-reactive protein; risk-increasing effect for soluble interleukin-6 receptor

October 2017 Briefing – Pathology

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Here are what the editors at HealthDay consider to be the most important developments in Pathology for October 2017. This roundup includes the latest...
Elevated levels of hepatitis B virus DNA and hepatitis B surface antigen are associated with increased risks of liver cancer

Hepatitis B Viral Load, Surface Antigen May ID Liver Cancer Risk

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Increased risk of liver cancer linked to hepatitis B DNA, surface antigen in a dose-response manner
The Centers for Medicare & Medicaid Services has launched an initiative to examine which provider regulations should be discarded or revamped amid concerns that the regulations are reducing the amount of time that physicians spend with patients

CMS Launches Initiative to Examine Impact of Regulations

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Officials set to travel country gathering information on impact of their regulations on physicians