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Transcription factor 7 like 2 (TCF7L2) genetic variants contribute to phenotypic heterogeneity of type 1 diabetes

Genetic Variants Tied to Type 1 Diabetes Heterogeneity

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TCF7L2 variants associated with single autoantibody, higher C-peptide, lower glucose
Higher early childhood intake of alpha-tocopherol is associated with lower odds of elevated mid-childhood alanine aminotransferase levels

Vitamin E in Early Childhood Tied to Lower ALT Levels Later

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Findings persist when early diet considered; strengthened when BMI z-score taken into account
Clinician suspicion has minimal accuracy for the diagnosis of Lyme disease

Clinician Suspicion Minimally Accurate for Lyme Disease

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12 percent of the children clinicians thought were unlikely to have Lyme disease had Lyme disease
A substantial number of patients diagnosed with incident cancer in the United States have a prior history of cancer

History of Prior Cancer Common in Newly Diagnosed Patients

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More than 18 percent of new cancer cases had a prior cancer, usually at a different site
New solutions are needed to address burnout among health care team members

New Workflows Have Potential to Address Provider Burnout

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Change fatigue is the leading cause of care team burnout, yet new solutions needed
Seemingly benign

Essay Adds to Discourse on Impact of Suggestive Jokes

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Authors say commonplace suggestive jokes normalize, dismiss sexual misconduct experiences
Single measles cases trigger coordinated public health action that is associated with considerable costs

Considerable Costs Incurred in Response to Single Measles Cases

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Public health costs of disease investigation for two single measles cases estimated at $49,769, $18,423
Spouses of female physicians are on average more educated and work more hours outside the home than spouses of male physicians

Female Physicians’ Spouses More Likely to Work

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May explain need for female physicians to make more personal and professional adjustments
Raw flour can be a source of outbreak of Shiga toxin-producing Escherichia coli infections

Raw Flour Can Be Source of Shiga Toxin-Producing E. coli

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On trace-back investigation, flour production facility ID'd as common point of contamination
Plasma N-terminal pro-B-type natriuretic peptide levels are significantly lower for black than white individuals

NTproBNP Levels Are Significantly Lower in Blacks

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Higher NTproBNP levels linked to increased risk of death; this association did not differ by race