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Immediate reduction of nicotine in cigarettes leads to significantly greater decreases in biomarkers of smoke exposure than gradual reductions in nicotine levels

Bigger Cut in Smoke Exposure for Immediate Nicotine Reduction

Smokers with immediate versus gradual reduction have significantly lower levels of smoke exposure
Breast cancer risk peaks around the 40s for BRCA1 mutation carriers and around the 50s for BRCA2 carriers

Family Hx, Mutation Position Key Variables in BRCA1/2 Cancer Risk

Study findings provide cancer risk patterns based on BRCA status using prospective data
Aedes mosquitoes in California can spread the Zika virus

Some California Mosquitoes Can Carry Zika Virus

Aedes aegypti mosquitoes found to transmit Zika virus
More American teens have diabetes or prediabetes than previously thought

Diabetes Rates for U.S. Teens Higher Than Previously Reported

Most young people unaware they have diabetes, prediabetes

Ruxolitinib Best for Glucocorticoid-Refractory, -Dependent GVHD

Overall response, failure-free survival, symptom response significantly greater with ruxolitinib versus control therapy

Listerine mouthwash may be potentially useful for gonorrhea control

Mouthwash May Be Useful for Gonorrhea Control

Listerine significantly reduces the amount of N. gonorrhoeae on the pharyngeal surface
Exome sequencing-based screening may identify pathogenic and likely pathogenic BRCA1/2 variants that might otherwise remain undetected

Genomic Screening Can ID Undetected BRCA1/2 Cancer Risk

82 percent of variant carriers identified in exome sequencing had not undergone prior testing
About one-quarter of adults with chronic kidney disease of unknown cause or familial nephropathy or hypertension have diagnostic mutations

Diagnostic Mutations ID’d in Chronic Kidney Disease Patients

Whole-exome sequencing identified diagnostic mutations, including PARN mutations, in two patients

AI Tool Allows Identification of Malignant Cells in Gliomas

CHARM can also distinguish isocitrate dehydrogenase-mutant tumors from wild type, and classify three types of molecularly defined gliomas

Following state health reform

Massachusetts Health Reform Tied to Decrease in Advanced Cancer

Findings seen for colorectal cancer, but no similar findings found for advanced breast cancer diagnoses