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A levonorgestrel-releasing intrauterine device is effective in the majority of patients undergoing conservative treatment for low-risk endometrial cancer and complex atypical hyperplasia

Levonorgestrel IUD Feasible for Low-Risk, Early Uterine Cancer

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Majority of women responded well and returned to normal histology in six months
For healthy adults and individuals with well-controlled type 2 diabetes

DPP-4 Inhibitor Has Dissociated Effects on β-Cell Function

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Single dose of sitagliptin linked to increases in standardized insulin secretion, active GIP, GLP-1
Switching dual antiplatelet therapy from aspirin plus ticagrelor or prasugrel to aspirin plus clopidogrel after acute coronary syndrome provides benefits regardless of initial platelet reactivity

Switching Dual Antiplatelet Therapy Beneficial After ACS

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Greatest benefit seen in patients with low on-treatment platelet reactivity
Patients with various rheumatic diseases have an increased risk of dementia

Rheumatic Diseases Associated With Increased Dementia Risk

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Statistical significance in Sjögren's syndrome, lupus, OA in females; SS, psoriatic arthritis, OA in males
For acute ischemic stroke

Gingko Biloba Extract Found Effective in Acute Ischemic Stroke

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GBE plus aspirin alleviates cognitive, neurological deficits with no effect on adverse, vascular events
Cancer therapies have direct effects on telomere length

Cancer Therapies May Trigger Aging Phenotypes in Survivors

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Chemotherapies, radiation have direct effects on telomere length, epigenetic modifications, microRNA
The U.S. Preventive Services Task Force (USPSTF) has found that the current evidence is inadequate to assess the benefits and harms of screening with electrocardiogram for atrial fibrillation in older adults; and for low-risk adults

USPSTF Reviews Use of ECG for Preventing A-Fib, CVD Events

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I statement for use of ECG in A-fib in seniors; D recommendation against ECG for reducing CVD risk
Children born to mothers with rheumatoid arthritis may have an increased risk of rheumatoid arthritis

RA Exposure In Utero Tied to Increased Disease Risk

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Children exposed to maternal rheumatoid arthritis have higher risk of thyroid disease, epilepsy, RA
Primary care providers will play an important role in preventing the next wave of HIV infections

Primary Care Crucial for Preventing New HIV Infections

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Increase in HIV cases among young, healthy adults, who are likely to turn to primary care for advice, tx
A targeted microbiome intervention

Microbiome Intervention With Niacin Aids Insulin Sensitivity

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Delayed-release microcapsules of nicotinic acid induce favorable microbiome changes