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Healthy older subjects display preserved neurogenesis in the Hippocampus

Preserved Neurogenesis in Hippocampus of Healthy Seniors

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Older adults have less angiogenesis, neuroplasticity; smaller quiescent progenitor pool in anterior-mid DG
Method of diagnosis

Breast Cancer Diagnosis, Therapy Differ in Women With Implants

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Palpable cancers often detected at smaller size in breasts with implants; higher rates of mastectomy
Testicular cancer survivors have metabolic abnormalities characterized by hypertension and increased low-density lipoprotein and total cholesterol

Metabolic Abnormalities Seen in Testicular Cancer Survivors

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HTN, increased LDL and total cholesterol levels; lower rates of decreased HDL levels, abdominal fat
Early aggressive action should be taken to prevent the spread of bacteria harboring unusual resistance genes

CDC: Aggressive Action Needed to Contain Antibiotic Resistance

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Bacteria harboring unusual resistance genes are widespread
Early-life epilepsy should be treated with the same urgency as pediatric cancer

Early-Life Epilepsy Should Be Urgently Treated With EBM

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Best diagnostics and evidence-based treatments should be used from the start of the disease
Anomalous brain development is evident among medication-naive preschoolers with attention-deficit/hyperactivity disorder

Anomalous Brain Structure ID’d in Preschoolers With ADHD

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Reductions in bilateral frontal, parietal, and temporal lobe gray matter volumes in ADHD
Overweight and obesity may be contributing to specific malignancies at younger ages

Overweight, Obesity Contributing to Cancers in Young Adults

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Murine models suggest excessive weight increases cancer incidence and accelerates development
Using CYP2C19 genotype-guided dual antiplatelet therapy selection is feasible in a real-world setting

Genotype-Guided Antiplatelet Therapy Feasible, Effective

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Genotype-guided therapy improves outcomes among CYP2C19 intermediate, poor metabolizers
The majority of caregivers of children with food allergy are willing to consider participation in clinical trials for food allergy immunotherapy

Most Parents Willing to Enroll Child in Food Allergen Trials

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Higher parental income only significant positive predictor of willingness to enroll child in trial

March 2018 Briefing – Pathology

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Here are what the editors at HealthDay consider to be the most important developments in Pathology for March 2018. This roundup includes the latest...