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The 70-gene signature assay affects treatment decisions among physicians treating patients identified as being at intermediate risk with the 21-gene assay

70-Gene Signature Impacts Treatment Decisions in Breast CA

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70-GS linked to change in treatment decisions for intermediate-risk patients based on 21-gene assay
Emergency departments are increasingly a major source of medical care in the United States

ERs Contribute Large Portion of Medical Care Delivery

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Percentage of care delivered by emergency departments increased between 1996 and 2010
Receipt of gifts from pharmaceutical companies is associated with more prescriptions per patient and more costly prescriptions

Gifts From Pharma Companies Influence Prescribing Behavior

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Clinicians who receive gifts write more prescriptions per patient, more costly and branded prescriptions
Resistance to antiretroviral therapy is threatening the recent gains of treatment in the rate of new HIV infections

HIV Drug Resistance Is Threatening Gains of Treatment

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WHO has proposed 5-point plan for monitoring, combating, and preventing drug resistance
Recommendations have been developed for trial of labor after cesarean delivery for women who wish to achieve a vaginal birth after cesarean delivery

Recommendations Developed for Trial of Labor After C-Section

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Most women with one previous cesarean with low-transverse incision are candidates for TOLAC
Direct-to-consumer genetic testing raises unique concerns and considerations

Concerns Surround Use of Direct-to-Consumer Genetic Testing

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Issues include limited knowledge about available tests, difficulty interpreting results, lack of oversight
Long-acting reversible contraceptives

New ACOG Guidance on Long-Acting Reversible Contraceptives

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Insertion of IUD should be offered after first-trimester uterine aspiration, on same day as abortion
The demand for fertility preservation is increasing

Demand for Fertility Preservation Increasing for Women

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Oocyte cryopreservation by vitrification provides highest yield, suitable when cancer tx can be delayed
Researchers may have uncovered the mechanism for chemotherapy-induced peripheral neuropathy related to paclitaxel

Mechanism ID’d for Chemo-Related Peripheral Neuropathy

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Paclitaxel triggers CIPN in part by altering IP3 receptor phosphorylation, intracellular calcium flux
Leptin appears to mediate the correlation between weight suppression and duration of illness in bulimia nervosa-syndrome

Researchers Study Mediating Role of Leptin in Bulimia

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Model in which longer illness duration contributed to leptin via weight suppression not supported