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For patients with moderate COVID-19

Convalescent Plasma Has Limited Benefit for Moderate COVID-19

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Randomized phase II trial shows no drop in progression to severe disease, all-cause deaths
Neonates with prolonged arterial line/central venous line use have fewer skin breaks and have significantly larger thalamic volumes early in life compared with those with restricted line use

Skin Breaks Drop With Prolonged AL/CVL Use in Neonates

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Larger thalamic volumes seen with prolonged arterial line, central venous line use and fewer skin breaks
COVID-19 may not cause a cytokine storm

Cytokines Not at ‘Storm’ Levels in Those With Severe COVID-19

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Levels in severely, critically ill COVID-19 patients much lower than in other inflammatory syndromes
A population-based risk algorithm performs well for predicting death and hospital admission due to COVID-19 in adults

Algorithm Predicts Death, Hospital Admission From COVID-19

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Final risk algorithm includes age, ethnicity, deprivation, body mass index, range of comorbidities
For moderately ill hospitalized patients with COVID-19

Tocilizumab Does Not Prevent Intubation, Death in COVID-19

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Intubation or death, disease worsening similar for tocilizumab, placebo in hospitalized patients
The number of COVID-19-related deaths may be underestimated

CDC: Number of COVID-19 Deaths May Be Underreported

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Only two-thirds of the nearly 300,000 excess deaths in 2020 are attributed to COVID-19
The first company to start a phase 3 trial of a COVID-19 vaccine reached its target of enrolling 30

U.S. COVID-19 Vaccine Trial Enrolls 30,000

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Moderna says it is on track to apply for FDA approval to market the vaccine in early December
In a move that widens the pool of people considered at risk for COVID-19 infection

CDC Broadens Definition of ‘Close Contact’ in Tracing COVID-19 Infections

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Change will likely have biggest impact in group settings where people are in repeated contact with others
Vaccine-related attributes and political characteristics are associated with preference for choosing a hypothetical COVID-19 vaccine

Vaccine Attributes Influence Readiness to Accept COVID-19 Shot

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Political considerations also influence preference for choosing a hypothetical COVID-19 vaccine
Vertebral fractures are a clinical marker of fragility and poor prognosis in patients with COVID-19

Vertebral Fractures Marker of Poorer Prognosis in COVID-19

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COVID-19 patients with vertebral fractures more often require noninvasive mechanical ventilation