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Hematology and Oncology

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Certain aspects of empathy improve during medical student training

Some Aspects of Empathy Improve During Medical Training

Decrease in empathy as assessed by JSPE, but overall cognitive empathy improved on the QCAE
Adherence to antibiotic guidelines for acute chest syndrome in children with sickle cell disease varies widely

Antibiotic Rx Adherence Varies Widely in Sickle Cell Care

Guideline-adherent therapy tied to fewer 30-day readmissions
The top 10 percent of privately insured U.S. adults without cancer using opioids account for most opioid use

Most Opioid Use Concentrated in Top 10 Percent of Users

Top 10 percent of users accounted for 76 percent of the total annual morphine equivalents
Adjuvant therapy with nivolumab is associated with longer recurrence-free survival than therapy with ipilimumab among patients undergoing resection of stage IIIB

Adjuvant Nivolumab Tops Ipilimumab in Melanoma

Longer recurrence-free survival for stage IIIB, IIIC, IV melanoma
Does being a physician carry a moral obligation to respond to calls for medical assistance on airplanes? That is the topic of an article published in the Sept. 12 issue of the Journal of the American Medical Association.

Are Physicians Obligated to Help on Planes?

One administrative physician explains his sense of obligation to help
For patients with resected stage III melanoma with BRAF V600E or V600K mutations

Dabrafenib, Trametinib Beneficial in Resected Melanoma

Rate of relapse-free survival up for resected stage III melanoma with BRAF V600E, V600K mutations
For patients with locally advanced

Longer Progression-Free Survival for Durvalumab in NSCLC

Longer median progression-free survival from randomization, higher response rate with durvalumab
The median cost of cancer drug development is $648.0 million

Median Cost of Cancer Drug Development $648.0 Million

Total revenue from sales of 10 drugs was $67.0 billion, with total R&D spending of $7.2 billion
Zika virus is an oncolytic virus that preferentially targets glioblastoma stem cells

Zika Virus Preferentially Targets Glioblastoma Stem Cells

ZIKV preferentially infects, kills GSCs relative to differentiated tumor progeny, normal neuronal cells
Neurological complications associated with anti-programmed death 1 antibody treatment have a diverse phenotype

Diverse Neurological Effects Linked to Anti-PD-1 Therapy

Complications seen after median of 5.5 cycles of anti-PD-1-inhibitors; include myopathy, neuropathies