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Hematology and Oncology

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In patients aged 80 and older with advanced non-small-cell lung cancer

Race, Education Level Predict CRT in Very Elderly With NSCLC

In elderly with stage III lung cancer, black race, lower-educated county tied to not receiving care
For patients who present with small

Active Surveillance Feasible for Small, Low-Grade Bladder Cancer

40 percent of active surveillance events were deemed to require treatment
Higher-intensity end-of-life care may be driven by financial incentives present in fee-for-service Medicare but not in the Veteran Affairs integrated system

Intense End-of-Life Care Found to Be Less Likely for VA Patients

Authors say results have important implications for the future of VA care, Medicare policy
There is a positive association between long-term night shift work and the risk of several common cancers for women

Long-Term Night Shift Work Linked to Cancer Risk in Women

Dose-response pattern seen, with increased risk of breast cancer for every five years of night shift work
The contributions of screening and treatment to decreases in breast cancer mortality vary by molecular subtype

Screening, Therapy Effect Varies by Breast CA Molecular Subtype

Reductions in breast cancer mortality linked to screening and treatment, but associations vary
TP53 pathogenic variants are overrepresented in children with acute lymphoblastic leukemia and are associated with worse outcomes

TP53 Variants Linked to Childhood ALL, Poor Outcomes

Carrying germline variants linked to decreased event-free, overall survival; higher risk of second cancers
There is an increased risk of developing cardiovascular disease among patients with idiopathic thrombocytopenic purpura

Idiopathic Thrombocytopenic Purpura Tied to Higher CVD Risk

Risk further increased among patients with ITP who undergo splenectomy
Hospitals that volunteered to be under financial incentives for more than a decade as part of the Premier Hospital Quality Incentive Demonstration do not have better process scores or lower mortality than hospitals where these incentives were implemented later under the Hospital Value-Based Purchasing program

For Hospitals, No Benefit for Early Adoption of Financial Incentives

Hospitals with early adoption do not have better process scores, lower mortality than late adopters
In both men and women in the United States

Cancer Death Rate Continuing to Decline in United States

Continuous drop in combined cancer death rate from 1991 to 2015, resulting in 2,378,600 fewer deaths
Fluorouracil application can reduce the risk of surgery for squamous cell carcinoma for one year among patients with a history of keratinocyte carcinomas

Fluorouracil Tied to Reduced Surgery for Squamous Cell CA

Reduced risk of squamous cell carcinoma, but not basal cell carcinoma, for one year in at-risk veterans