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Genomic recurrence score testing using a 21-gene assay is associated with decreased cancer care costs in real-world practice among certain patients with breast cancer who would otherwise receive standard chemotherapy

Recurrence Score May Cut Costs for High-Risk Breast Cancer Care

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Testing with 21-gene assay linked to lower relative, absolute costs among high-risk patients
From 2000 to 2015

2000 to 2015 Saw Increase in Liver Cancer Mortality

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Increase generally steeper in less educated women; confined to men with ≤15 years education
Poor emotional health is common among caregivers of older cancer patients

Caregiving for Older Cancer Patients Takes Emotional Toll

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Poorer patient health tied to higher levels of caregiver distress among informal caregivers
For U.S. adults

Dietary Supplement Use Not Linked to Mortality Benefits

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Excess calcium intake may increase risk for cancer death; link related to supplemental calcium intake
Continued smoking among patients with cancer and the associated increase in attributable first-line cancer treatment failure is tied to significant incremental costs for subsequent cancer treatments

Continued Smoking Among Cancer Patients Ups Costs by $3.4B

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Estimates based on additional treatment following higher failure risk for first-line cancer treatment
The latest edition of the American College of Radiology Appropriateness Criteria has been released and includes 188 diagnostic imaging and interventional radiology topics

New, Revised Topics Released in ACR Appropriateness Criteria

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New topics relate to clinically suspected vascular malformation of extremities, gestational trophoblastic disease
Only one-quarter of those with breast cancer and one-third with ovarian cancer undergo genetic testing

Genetic Testing Underused in Breast, Ovarian Cancer

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Pathogenic variants ID'd in 7.8 percent of patients with breast cancer, 14.5 percent with ovarian cancer
Preventive drugs are frequently used in the last year of life among older adults with cancer

Preventive Drugs Often Used in Last Year of a Cancer Patient’s Life

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Preventive drugs, including antihypertensives and statins, frequently continued until final month of life
More than one-third of U.S. adults in recovery for alcohol and other drug use have health problems related to previous substance use

Alcohol, Drug Misuse Tied to Long-Term Health Problems

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Despite recovery, chronic physical disease continues to impact quality of life, life expectancy
Four evidence-based guidance statements on breast cancer screening have been developed by the American College of Physicians and published online April 9 in the Annals of Internal Medicine.

Guidance Statements Issued for Breast Cancer Screening

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Clinicians should discuss mammography with patients aged 40 to 49, discontinue screening for those ≥75