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Moderna CEO Says Fourth COVID-19 Dose May Be Needed Next Fall

FDA Limits Use of J&J COVID-19 Vaccine Due to Blood Clot Risk

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With safer two-dose vaccines such as Pfizer and Moderna widely available, the one-dose J&J shot should be limited

More than 15 percent of American adults are physically inactive

CDC: Many Americans Are Inactive, With Southerners Faring Worse

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Agency releases new estimates of physical inactivity across states and U.S. territories
An intervention involving bilingual/bicultural lay health educator education can increase colorectal cancer screening among Hmong-Americans

Tailored Lay Health Educator Program Ups CRC Screening

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Bilingual/bicultural lay health educator education can increase screening among Hmong-Americans
For patients in intensive care units who need a catheter

Subclavian Vein Catheterization Beats Jugular, Femoral Placement

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Reduces risk of blood infection, deep-vein thrombosis among critically ill
Transcription factors seem to operate across gene loci

TFs Operate Across Gene Loci Within Disease Phenotypes

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Epstein-Barr virus EBNA2 protein binds to multiple loci of genome, increasing risk of 7 serious diseases
Restricting blood transfusion guidelines may save both lives and money

CHEST: Blood Transfusion Practices Should Be Revisited

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Study looks at transfusion practices of intensive care providers in a typical tertiary hospital
Immune checkpoint inhibitors show promise in treating advanced melanoma

AACR: Immune Checkpoint Inhibitors Promising in Melanoma

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Pembrolizumab, ipilimumab, and other medications harness immune cells to target cancers
Current low-intensity smokers have an increased risk for respiratory and lung cancer mortality

Respiratory, Lung Cancer Death Up Even With Low-Intensity Smoking

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Risks for respiratory and lung cancer mortality increased for those smoking <10 cigarettes per day
High-dose crizanlizumab treatment is associated with a significantly lower rate of sickle cell-related pain crises than placebo

ASH: Lower Rate of Sickle Cell Pain Crises With Crizanlizumab

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Lower rate of crises per year; longer median time to first, second crises with high-dose therapy
Moderate and severe obstructive sleep apnea are associated with elevated blood coagulability markers

Moderate, Severe OSA Linked to Elevated Blood Coagulability

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Increases in prothrombin time in seconds and as international normalized ratio for OSA vs controls