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Immediate or delayed differences in adverse event rates were seen after generic commercialization of three antihypertensive drugs

Commercialization of Generics Impacts Adverse Event Rates

Adverse events up for generic users of losartan, valsartan, candesartan in month of commercialization
Many basic scientists and clinical researchers support somatic genome editing in adults for prevention of serious disease but not for human enhancement; they also believe the public should be consulted before any clinical application of germline gene editing proceeds

Scientists Support Genome Editing to Prevent Disease

Majority of survey respondents support gene editing to treat diseases but not human enhancement
Treatment with long-acting muscarinic antagonists plus long-acting β-agonists is associated with fewer exacerbation events in patients with chronic obstructive pulmonary disease

LAMA Plus LABA Tied to Fewer Exacerbations in Stable COPD

Also might result in greater improvement in FEV1 than LABA plus corticosteroids
Nonvalvular atrial fibrillation patients who take non-vitamin K oral anticoagulants along with certain other medications are at increased risk for major bleeding

Anticoagulants With Other Drugs Raise Bleeding Risk in AF

And antithrobotic medications linked to higher rate of hematuria-related events in older adults
The burden of overweight- and obesity-related cancer is high in the United States

Rate of Obesity-, Overweight-Related Cancers High in the U.S.

40 percent of cancer diagnoses tied to extra weight; rate higher in older individuals, females
Many female physicians report feeling disadvantaged when negotiating contracts and feel that they are assessed for promotion using different criteria than those used for men

Pay Inequality, Work-Life Balance Top Concerns for Female Docs

Despite challenges, 86 percent say they are likely to continue practicing as doctors for rest of career
For patients undergoing total hip arthroplasty

Patient Factors Differ for Surgical, All-Cause Readmission

Highest odds of return to theater after hip surgery tied to drug abuse, psychoses, dementia, depression
General practitioners are less likely to support cessation of smoking in patients with cancer than in those with coronary heart disease

Smoking Cessation Support Less Likely for Cancer Patients

General practitioners less likely to support smoking cessation in patients with cancer than with CHD
For patients with acute heart failure admitted to the emergency department

ER Risk Score Predicts 30-Day Mortality in Acute Heart Failure

Risk score based on 13 independent risk factors has excellent discrimination and calibration
Prescription opioid-related inpatient and emergency department discharges have decreased since 2010

Hospital Discharges for Prescription Opioids Have Fallen

But inpatient and ED discharges related to heroin have increased in past decade