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Parkinson's disease patients with glucocerebrosidase gene mutations have increased risk for dementia and death

Dementia, Mortality Risk Up for GBA Carriers With Parkinson’s

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Mortality risk remained greater in carriers after introduction of dementia as time-dependent covariate
An experimental drug

Laquinimod Appears Effective Against Multiple Sclerosis

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Animal study indicates laquinimod slows disease progression, but human trials needed
Gonorrhea samples taken last spring from seven patients in Honolulu showed resistance to azithromycin at dramatically higher levels than typically seen in the United States

CDC: Higher Levels of Resistance Seen in Gonorrhea Treatment

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First cluster of cases to show increased resistance to both azithromycin and ceftriaxone
A new type of immunotherapy involving natural killer cells may help treat acute myeloid leukemia patients

Immunotherapy Promising for Tx of Acute Myeloid Leukemia

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In preliminary trial, four of nine patients with acute myeloid leukemia had complete remission
For adults with acute Plasmodium vivax or P. falciparum

KAF156 Active for Adults With Vivax, Falciparum Malaria

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Antimalarial activity seen with multiple and single dose, with no serious adverse events
For preterm infants with early respiratory distress

Tx Failure Up for High-Flow Therapy Versus CPAP in Preemies

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Significantly higher rate of treatment failure than CPAP in preterm infants with respiratory distress
In obese patients

Changes in Blood Microbiota in Obese With Liver Fibrosis

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Among obese patients, 16S rDNA concentration significantly higher for those with liver fibrosis
Congenital brain abnormalities are similar for confirmed and presumed Zika infections

Findings to Help Radiologists ID Zika Virus Infection at Imaging

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Similar brain abnormalities seen in confirmed and presumed congenital Zika infections
For patients with type 1 diabetes

Decline in eGFR Mainly Linear in Type 1 Diabetes

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Trajectories in eGRF decline were linear for about 87 percent of patients, accelerating for 6 percent
Among children with persistent asthma

High Prevalence of Allergic Sensitization in Pediatric Asthma

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Microarray methods provide new information in 47 percent of sensitized children