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Metformin use in combination with docetaxel chemotherapy does not significantly improve survival in patients with diabetes and metastatic castration-resistant prostate cancer

Metformin Use Does Not Increase Prostate Cancer Survival

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Drug given in combination with docetaxel chemotherapy in patients with metastatic disease
Asymptomatic carriers of toxigenic Clostridium difficile in hospitals increase infection risk in other patients

Asymptomatic C. difficile Ups Risk for Other Hospital Patients

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Amount of exposure to asymptomatic carriers increases risk of infection
The TRASER (Total Reflection Amplification of Spontaneous Emission Radiation) device is a safe and effective option for treatment of nasal telangiectasias

Novel Laser Device Effective for Nasal Telangiectasia Treatment

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Treatment effective in all patients, with most needing only one treatment session
Twin pregnancies in older women (at least 45 years of age) overall have favorable outcomes but are associated with high rates of some complications

Overall Favorable Outcomes for Twin Pregnancies in Moms 45+

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But high rates of cesarean delivery, preeclampsia, and gestational diabetes seen
A questionnaire-based approach seems to be valid for identifying adults in the intensive care unit with a frailty phenotype

Questionnaire-Based Approach Valid for Identifying Frailty

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Frailty phenotype with three or more markers predicts death or increased disability at six months
Mindfulness practice during chemotherapy can reduce the blunting of neuroendocrine profiles typically observed in cancer patients

Mindfulness Practice Reduces Cortisol Blunting During Chemo

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Findings in colorectal cancer patients using mindfulness practice at start of chemo sessions
Higher serum fasting insulin and insulin resistance predict poorer verbal fluency and a steeper decline in future verbal fluency

Insulin Resistance Predicts Later Cognitive Decline

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Higher serum fasting insulin predicts future decline in verbal fluency
Immediate cholecystectomy may not always be necessary for patients with acute biliary pancreatitis

Surgery May Not Be Necessary in Acute Biliary Pancreatitis

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Research suggests factors may predict need for immediate cholecystectomy
Music therapy interventions can favorably affect pain perceptions in patients recovering from spine surgery

Music Therapy Relieves Post-Op Pain in Spinal Surgery Patients

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Live tunes, singing, rhythmic drumming appeared to help ease discomfort after spinal surgery
Intradetrusor injection of onabotulinumtoxin A is safe and effective for bladder chemodenervation in overactive bladder

Review Explores Botulinum Toxin in Overactive Bladder Treatment

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Liposome encapsulated onabotulinumtoxin A reduces urinary frequency, urgency, not incontinence