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There is a correlation for documented penicillin allergy with increased risk of methicillin-resistant Staphylococcus aureus and Clostridium difficile

Penicillin Allergy Linked to MRSA, C. Difficile Risk

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Association is mediated by increased use of β-lactam alternative antibiotics
The quality of atrial fibrillation/atrial flutter trials is variable

Variation in Quality of Trials for Atrial Fibrillation, Flutter

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Most common trial endpoint is AF/AFL recurrence; rates of primary clinical endpoints are low
New laws and regulations designed to limit the use of prescription narcotics may further constrain doctors' ability to treat patients

New Rules May Constrain Docs’ Ability to Treat Chronic Pain

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Limitations on the use of prescription narcotics could complicate patient treatment
Caring for deteriorating patients while precepting novice nurses requires a balancing of teaching and patient care roles

Nurse Preceptors Must Balance Teaching, Patient Care

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Finding the balance includes supporting the novice, knowing when to step in, and debriefing
The U.S. Food and Drug Administration has approved Epidiolex oral solution for treatment of seizures associated with Lennox-Gastaut syndrome and Dravet syndrome for patients age 2 years and older.

FDA Approves Epidiolex for Severe Forms of Epilepsy

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Cannabidiol oral solution approved for patients 2 and older with Lennox-Gastaut and Dravet syndromes
A radiomic low-dose computed tomography-based approach is promising for indeterminate screen-detected nodule characterization

Radiomic Model Approach for Characterizing Nodules Promising

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Eight quantitative radiologic features result in optimism-corrected area under curve of 0.939
All expectant families should have a pediatric prenatal visit

Prenatal Pediatric Visit Recommended for Expectant Families

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Visit provides unique opportunity to address relationship between family and pediatric practice
Midlife fitness is associated with reduced risk of depression in later life and with reductions in the risk of cardiovascular disease (CVD) mortality and CVD mortality after later-life depression

Midlife Fitness Linked to Lower Risk of Depression, CVD Death

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Reduction also seen in CVD mortality with antecedent depression in association with high fitness level
Greater reproducibility and higher concordance are seen for melanoma staging with the American Joint Committee on Cancer (AJCC) classification of cancer staging

New Guidelines Increase Melanoma Staging Reproducibility

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Greater reproducibility and higher concordance for melanoma staging with implementation of AJCC 8
Genetic risk and lifestyle are independent predictors of incident cardiovascular disease and diabetes

Genetic Risk, Lifestyle Predict CVD, Diabetes Independently

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No interactions seen for any outcome; log-additive effect on risk of developing cardiovascular disease