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Monthly Archives: August 2015

Use of dipeptidyl peptidase-4 inhibitors in type 2 diabetes is tied to severe joint pain in some patients

FDA Warns of Joint Pain Tied to DPP-4 Inhibitors

Agency advises users with such symptoms to contact their doctor
Alcohol poses a far greater threat to children than many parents may realize

AAP: In Office Visits, Ask Every Adolescent About Alcohol Use

Many starting at younger ages, so more likely to binge drink
Infants at high risk for peanut allergies should be given foods containing peanuts before they reach the age of 1 year

Consensus for Early Peanut Exposure in High-Risk Infants

Interim guidance issued in response to study finding exposure lowered chances of allergy by 80 percent
Transvaginal sonography

Ultrasound, MRI Comparable for Cervical Cancer Staging

Transvaginal sonography, a feasible and economic imaging modality
For patients who require permanent single-chamber ventricular pacing

Leadless Cardiac Pacemaker Deemed Safe, Effective

In most patients, leadless cardiac pacemaker met prespecified pacing and sensing requirements
Intravenous cyclosporine does not improve outcomes versus placebo in patients with anterior ST-segment elevation myocardial infarction who had been referred for primary percutaneous coronary intervention. The findings were published online Aug. 30 in the New England Journal of Medicine to coincide with the annual European Society of Cardiology Congress

Intravenous Cyclosporine Doesn’t Improve STEMI Outcomes

For patients undergoing PCI, cyclosporine doesn't prevent adverse left ventricular remodeling at 1 year
The risk of osteonecrosis of the jaw is highest in association with intravenous bisphosphonate use

Osteonecrosis of Jaw Risk Highest for IV Bisphosphonate Use

High risk for zoledronate, denosumab mainly in prevention of skeletal-related events
Femtosecond laser-assisted cataract surgery is associated with improved outcomes compared with conventional cataract surgery

Outcomes Up for Femtosecond Laser-Assisted Cataract Sx

Significantly improved accuracy and repeatability of capsulorhexis compared with conventional sx
Recent research indicates that many pregnant women have a median urinary iodine concentration below the recommended level

Lack of Sufficient Iodine Nutrition Common During Pregnancy

More targeted intervention strategies needed to optimize iodine nutrition during pregnancy
Nonalbuminuric chronic kidney disease is associated with increased risk of cardiovascular disease and all-cause mortality

Nonalbuminuric CKD Ups Cardiovascular Morbidity in T1DM

Also linked to increase in all-cause mortality, but not albuminuria or end-stage renal disease