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Direct-acting antiviral prophylaxis is safe and prevents chronic hepatitis C virus (HCV) infection after kidney transplantation from HCV-infected donors to noninfected recipients

Prophylaxis Can Prevent HCV Infection in Kidney Recipients

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With direct-acting antivirals, no adverse events seen when kidneys came from HCV-infected donors
Domperidone is well tolerated and effective in producing a moderate short-term increase in expressed breast milk volume among mothers of preterm infants

Domperidone Tied to Modest Increase in Breast Milk Supply

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Mothers of preterm infants with insufficient milk supply had 88.3 mL/day increase in milk volume
The global costs of diabetes are high and will increase substantially by 2030

Global Costs of Diabetes Will Continue Rising Through 2030

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Global economic burden will not decrease, even if international targets are met
Low-dose dexmedetomidine significantly reduces delirium in critically ill adults

Dexmedetomidine Found to Prevent Delirium in Critically Ill

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Patients receiving low-dose dexmedetomidine report no changes in sleep quality
Guidance has been developed for hemoglobin A1c targets for glycemic control among nonpregnant adults with type 2 diabetes; the guidance statement was published online March 6 in the Annals of Internal Medicine.

ACP Updates Guidance for HbA1c Targets for Adults With T2DM

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Clinicians should personalize glycemic control goals; aim for HbA1c of 7 to 8 percent for most adults
Calcium supplements

Calcium ± Vit D Supplements Up Risk of Colon Adenomas, Polyps

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Late effect findings of sessile serrated adenomas, polyps in those taking calcium with/without vitamin D

February 2018 Briefing – Pharmacy

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Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for February 2018. This roundup includes the latest...
Women with current asthma who use intermittent reliever treatment with short-acting beta-agonists have reduced fertility

Female Infertility Tied to Asthma Managed With Rescue Inhalers

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No link to infertility for those with former asthma, or for those with asthma preventer medications
For individual patients with type 2 diabetes mellitus

Treatment Effect of Fenofibrate Varies in Patients With T2DM

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Treatment effect is greater in patients with dyslipidemia; absolute risk reduction of 2.15 percent
A low risk of serotonin syndrome is seen in association with concomitant use of triptans and selective serotonin reuptake inhibitor or selective norepinephrine reuptake inhibitor antidepressants

Low Risk of Serotonin Syndrome for Triptans + SSRI/SNRI

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Researchers question FDA advisory warning on risk of concomitant use