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A recall of the widely used diabetes drug metformin was announced by drug maker Apotex due to possible high levels of N-Nitrosodimethylamine

Metformin Recalled Due to Potential Cancer-Causing Chemical

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Recall is for all lots of metformin hydrochloride extended-release tablets 500 mg from Apotex
Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of May 25 to 29

Physician’s Briefing Weekly Coronavirus Roundup

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Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of...
For men with advanced prostate cancer

ASCO: Relugolix Superior to Leuprolide in Advanced Prostate Cancer

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And, enzalutamide improves median overall survival in nonmetastatic, castration-resistant prostate cancer
There seems to be no significant difference between a five- and 10-day course of remdesivir for patients with severe COVID-19 not requiring mechanical ventilation

Five-Day Course of Remdesivir Beneficial in Severe COVID-19

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No significant difference seen in five-, 10-day course for severe COVID-19 without mechanical ventilation
For adolescent and young adult patients with Hodgkin lymphoma

Outcomes Equal for AYA Hodgkin Therapy at Peds, Adult Centers

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Treatment strategies differ, but outcomes equivalent among adolescent, young adult Hodgkin patients
Worldwide more physicians are using remdesivir to treat COVID-19 patients

Remdesivir Use Growing Globally in COVID-19 Patients

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Yet, most physicians believe it is only moderately effective, better used earlier than official guidelines recommend
From 2004 to 2017

AAOS: Opioid Prescribing Down for Minor Ortho Injuries in Youth

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However, 54.3 percent of patients received at least one dose of opioid during ED or clinic visit
Insulin infusion helps achieve glycemic targets and may reduce the risk for poor outcomes in patients with hyperglycemia and COVID-19

Improving Glycemic Control May Also Aid COVID-19 Outcomes

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Insulin infusion may reduce risk for severe disease in those with hyperglycemia and COVID-19
The treatment effects of early comprehensive disease-modifying pharmacological therapy are considerable for patients with heart failure with reduced ejection fraction

Disease-Modifying Drug Regimen May Offer Benefit in Heart Failure

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Lower risk for cardiovascular death or hospital admission seen in HF with reduced ejection fraction
A total of 9.5 percent of persons were uninsured from January through June 2019

9.5 Percent Uninsured in U.S. From January Through June 2019

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Overall, 13.7 percent of adults aged 18 to 64, 4.4 percent of children aged 0 to 17 were uninsured