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A large clinical trial of the first U.S. COVID-19 vaccine could begin next month

First Large Clinical Trial of COVID-19 Vaccine in U.S. Could Begin in July

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Trial will assess effectiveness of vaccine, include 30,000 volunteers who will receive either vaccine or placebo
Recent cannabis use is not associated with acute ischemic stroke

Recent Cannabis Use Not Linked to Acute Ischemic Stroke

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After adjustment for confounding variables including age, race, cardiac condition, no link observed
Obesity is the most common comorbidity among children and adolescents with COVID-19 and is associated with disease severity

Obesity Linked to Greater Severity of Pediatric COVID-19

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Obesity is significantly associated with mechanical ventilation in children aged 2 years and older
Pooled data from recent studies show that women with acute stroke are less likely to be treated with intravenous thrombolysis compared with men

Treatment Gap Remains in Stroke Care Between Men and Women

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Size of this difference has narrowed compared with studies published before 2008
In another troubling sign that the spread of COVID-19 might be accelerating

Nine U.S. States Seeing Spikes in COVID-19 Hospitalizations

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Hospitalization data challenge the notion that spike in new cases is solely because of increased testing
A study to assess several drugs currently being used to treat COVID-19 in infants

Study Will Assess Drugs Used to Treat Young COVID-19 Patients

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Findings will be used to refine drug dosing and improve safety for young patients with COVID-19
Low-dose aspirin significantly lowers cardiovascular disease risk but increases the risk for bleeding

Low-Dose Aspirin Lowers CVD Risk but Raises Bleeding Risk

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Authors used umbrella review method to explore health outcomes associated with low-dose aspirin
Prostate cancer clinical trial participants are overwhelmingly white

Prostate Cancer Trial Participants Overwhelmingly White

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Since 1990, proportion of white participants in prostate cancer clinical trials has remained >80 percent
Filling an opioid prescription in the postpartum period is associated with an increased risk for serious opioid-related events

Filling Opioid Rx Postpartum Ups Serious Opioid-Related Events

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Serious opioid-related event rate increased with increasing number of postpartum opioid prescriptions
Screening for anxiety is recommended for women and adolescent girls

WPSI Advises Screening for Anxiety in Women, Teen Girls

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Diagnostic accuracy moderate to high for screening for anxiety; CBT and antianxiety meds beneficial