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For children and adolescents with migraine

Amitriptyline, Topiramate Don’t Cut Pediatric Migraine vs Placebo

No reduction in headache frequency or headache-related disability compared with placebo
Topiramate (Topamax) used for migraine headaches has been linked to increased odds of eating disorders in some teens. The report was published online April 6 in Pediatrics.

Migraine Medication Linked to Eating Disorders in Teens

Case reports don't prove the medicine caused problems, however