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AI Model for Early Prediction of Sepsis Improves Outcomes

Benefits include significant reduction in mortality and significant increase in sepsis bundle compliance

Novel Criteria Validated for Pediatric Sepsis, Septic Shock

Two studies describe development and validation of Phoenix criteria for identifying sepsis, septic shock in children

Limited English Proficiency Not Linked to Sepsis Mortality Overall

In subgroup analysis, LEP was associated with increased mortality among the non-Hispanic White subgroup

Placental Swabs Yield Highest Number of Potential Pathogens

37 percent of placental swabs yielded potential pathogens compared with 2 percent of blood cultures

Landiolol Does Not Reduce Organ Failure in Septic Shock Patients With Tachycardia

Mean Sequential Organ Failure Assessment score did not differ for those receiving landiolol and standard care

In-Hospital Mortality Evaluated for SARS-CoV-2-Linked Sepsis

March 2020 to November 2022 saw decline in crude in-hospital mortality for SARS-CoV-2-linked sepsis from 33.4 to 14.9 percent

Factors ID’d That Increase Risk for Mechanical Ventilation With Sepsis

However, risk factors change depending on time from diagnosis and comorbidities

Opportunities Exist for Improving Hospital-Based Sepsis Programs With New CDC Guidance

73 percent of hospitals have a committee that monitors and reviews sepsis care, with prevalence varying by hospital size

Continuous Meropenem No Benefit in Critically Ill Patients With Sepsis

No improvement seen in composite of all-cause mortality and emergence of pandrug- or extensively drug-resistant bacteria

Hydrocortisone Does Not Reduce 90-Day Mortality in Septic Shock

Small reduction in mortality seen with use of hydrocortisone with fludrocortisone