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Older adults with type 1 diabetes mellitus spend more than an hour per day in the hypoglycemic range

ENDO: Older T1DM Patients Often Unaware of Hypoglycemic Status

Impaired awareness of hypoglycemia tied to greater amounts of time spent with glucose <70, <54 mg/dL
Authors of a paper recently published in the Journal of the American Geriatrics Society describe factors that influenced the new National Institute of Health policy that requires funded scholars to eliminate arbitrary age limits in their work.

Influences on New NIH Policy for Age Limits in Research Explored

'Inclusion Across the Lifespan' policy eliminates non-risk-justified age limits on research participants
Almost half of elderly patients newly diagnosed with acute lymphoblastic leukemia do not receive treatment

Only About Half of Elderly Newly Diagnosed With ALL Receive Tx

53.5 percent receive treatment within 90 days; 32.4 percent receive chemo without tyrosine kinase inhibitors
From 2004 to 2017

2004 to 2017 Saw Increase in Fractures for Elderly Dog Walkers

Most patients sustained hip fractures; more than one-quarter of patients required admission
Older adults who are witnessed to have sleep apnea have increased accumulations of tau in the entorhinal cortex

AAN: Sleep Apnea Tied to Higher Cortical Tau Levels in Seniors

Estimated 0.049 elevation seen in the entorhinal cortex tau standardized uptake value ratio
Recommending pneumococcal vaccination for all 50-year-olds prevents the most disease in underserved minorities and the general population

Pneumococcal Vaccination at Age 50 Prevents the Most Disease

But cost of giving pneumococcal vaccines to all 50-year-olds exceeds $250,000 per QALY
Delaying or withholding antibiotics for older patients with a urinary tract infection is associated with an increase in bloodstream infection and all-cause mortality

Antibiotic Delay Leads to Increased Risks in Seniors With UTI

No antibiotics, deferred antibiotics tied to increase in bloodstream infection, all-cause mortality
In older adults

CVD Does Not Modify Depression-Mortality Link in Elderly

Depression tied to higher death risk in older adults; CVD explains just small fraction of excess mortality
From 2003 to 2016

Improved Outcomes Seen With Liver Grafts From Older Donors

However, liver graft discard from older donors remained increased from 2003 to 2016
Older patients with severe frailty undergoing transcatheter aortic valve replacement and surgical aortic valve replacement frequently experience subsequent functional decline or lack of improvement

Functional Decline Seen for Many Frail Patients After TAVR, SAVR

Older patients with severe frailty often have decline or lack of improvement after the procedures