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Tag: Prescription Drugs

For patients undergoing drug-eluting stent placement

High Rate of Clopidogrel Non-Adherence After DES Placement

Based on one-year refill data, 34 percent of patients had proportion of days covered <80 percent
Use of a faulty device in a regulatory drug trial has raised questions relating to rivaroxaban use

Safety Issues Raised in Key Trial Supporting Rivaroxaban Use

Defective point-of-care device used in warfarin arm of ROCKET AF trial calls results into question
Patients with minimal exposure to benzodiazepine have a slightly increased risk of dementia

Minimal Benzodiazepine Exposure May Up Dementia Risk

However, higher benzodiazepine use is not associated with more rapid cognitive decline
Acetazolamide does not differ from placebo in effect on the duration of invasive mechanical ventilation in patients with chronic obstructive pulmonary disease

Intubation Duration for COPD Unchanged by Acetazolamide

Randomized trial shows no difference vs placebo in duration of invasive mechanical ventilation
For obese women

Antenatal Metformin Cuts Maternal Weight Gain in Obese

Findings among women without diabetes with BMI of >35; no reduction in neonatal birth weight
A protein preload enhances the glucose-lowering efficacy of vildagliptin in type 2 diabetes

Protein Preload Boosts Vildagliptin’s Effects in Diabetes

Small whey preload augments plasma intact GLP-1 levels, slows gastric emptying
Tips for increasing patient adherence to treatment plans include patient engagement and addressing barriers to adherence

Tips Presented for Encouraging Treatment Adherence

Broad approach recommended, which includes patient engagement and addressing barriers
For adults with symptomatic chronic sinusitis and nasal polyposis refractory to intranasal corticosteroids

Subcutaneous Dupilumab Reduces Nasal Polyp Burden

Greater reduction for addition of dupilumab to mometasone furoate nasal spray in chronic sinusitis
Some clinical departments tend to undertreat when prescribing statins

Many Physicians Show Tendency to Undertreat With Statins

Target levels more likely to be achieved in departments that prescribe more statins
Reduction in albuminuria with the renin inhibitor aliskiren may be too small to confer clinical benefit in patients with type 2 diabetes

No Benefit From Aliskiren-Tied Drops in Albuminuria

Overall albuminuria drop may be too small for cardiovascular, renal risk protection