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FDA Approves Wegovy to Lower Risk for CVD Events in Patients With Obesity

Agency's action could widen access to the drug if more insurance companies decide to cover it

Survival Up With Enfortumab Vedotin + Pembrolizumab in Urothelial Cancer

Significantly longer progression-free and overall survival seen in patients with previously untreated locally advanced or metastatic urothelial carcinoma

Benralizumab Noninferior to Mepolizumab for Eosinophilic Granulomatosis With Polyangiitis

Benralizumab is noninferior, but not superior, for adults with eosinophilic granulomatosis with polyangiitis receiving standard care

Tacrolimus Microemulsion Has Good Efficacy, Safety for Scalp Psoriasis

Investigator Global Assessment of 0 or 1 occurred in significantly more patients receiving tacrolimus microemulsion versus placebo

Mixed Digital Intervention Increases HIV Prevention Adherence in Young People

Combo of one-on-one telehealth coaching, peer support forums, and automated text messages can double PrEP uptake

2015 to 2021 Saw Marked Rise in PCSK9 Inhibitor Utilization

Yet prescription rates remain substantially lower than that seen for other guideline-recommended cardiometabolic therapies

Top-Down Treatment Superior for Crohn Disease

One-year outcomes better with early combined infliximab + immunomodulator vs. accelerated step-up treatment

Exercise Key to Maintaining Weight Loss After Stopping GLP-1 Receptor Agonists

Findings seen for body weight, body fat percentage, weight loss, and weight regain

Prenatal Exposure to Antiseizure Meds May Not Increase Epilepsy Risk in Children

Risk for epilepsy similar for siblings who were exposed and unexposed to valproate in pregnancy

Enobosarm Has Antitumor Activity in ER-Positive, HER2-Negative Advanced Breast Cancer

At 24 weeks, 32 and 29 percent of patients in the 9-mg and 18-mg groups had clinical benefit