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Tag: Prescription Drugs

For men with non-metastatic castration-resistant prostate cancer

Apalutamide Active in Castration-Resistant Prostate Cancer

Apalutamide prolongs metastasis-free survival in non-metastatic castration-resistant prostate cancer
Compliance with guideline-directed medical therapy is low

Guideline-Directed Medical Tx Adherence Low Post CABG

Compliance higher in PCI than CABG, but remains low in contemporary clinical trials
Once-daily treatment with glecaprevir-pibrentasvir appears safe and effective for the treatment of hepatitis C virus genotype 1 or 3

Glecaprevir-Pibrentasvir Effective Treatment for HCV Genotypes 1, 3

Once-daily treatment for eight or 12 weeks yields high rates of sustained virologic response
Glucagon is being underutilized in the prehospital and outpatient setting

Glucagon Underutilized in Prehospital, Emergency Settings

Diabetic problem often incorrectly coded by dispatch; paramedic access to give glucagon also an issue
Pharmacist feedback and education is effective at reducing prescription writing errors by junior doctors in an inpatient setting

Pharmacist Education May Cut Junior Doctor Prescription Errors

Regular and targeted feedback by pharmacists reduces Rx errors; effect of e-learning tools unclear
For patients with intermediate risk of cardiovascular disease

ASA: Combo of BP, Cholesterol Meds Tied to Reduced Stroke Risk

44 percent drop in stroke for those with intermediate CVD risk receiving candesartan/HCTZ, rosuvastatin
For patients with dementia with Lewy bodies

Adjunct Zonisamide Beneficial in Dementia With Lewy Bodies

Zonisamide as an adjunct to levodopa improves parkinsonism without worsening cognitive function
Prior authorization requirements are greater for proprotein convertase subtilisin/kexin type 9 inhibitors than for other cardiometabolic drugs

Greater Prior Authorization Requirements Seen for PCSK9i Rx

PA requirements are more extensive for PCSK9is than for other cardiometabolic drugs
Doxylamine-pyridoxine may be beneficial for nausea and vomiting symptoms in early pregnancy

Value of Doxylamine-Pyridoxine Questioned in Early Pregnancy

Greater improvement in symptom scores versus placebo, but clinical relevance unclear
A case of remission of psoriasis after treatment of chronic hepatitis C virus has been described in a research letter published online Jan. 16 in the Annals of Internal Medicine.

Psoriasis Remission Described After Hepatitis C Virus Treatment

Case report: After initiation of ledipasvir-sofosbuvir, HCV RNA decreased, and skin lesions improved