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Tag: Prescription Drugs

The estimated annual cost of drug-related morbidity and mortality resulting from nonoptimized medication therapy is more than half a trillion dollars in the United States

Nonoptimized Drug Therapy Costs More Than $500 Billion Annually

After initial Rx use, average cost of individual having treatment failure, new medical problem over $2,000
Pembrolizumab is associated with significantly longer recurrence-free survival than placebo as adjuvant therapy for high-risk stage III melanoma

Adjuvant Pembrolizumab Beneficial in Stage III Melanoma

Pembrolizumab linked to significantly longer recurrence-free survival at 15-month follow-up
For patients with breast cancer

Endocrine Therapy-Induced Alopecia Seen in Breast Cancer

92 percent had grade 1 severity alopecia with endocrine tx; pattern similar to androgenetic alopecia
Physicians receiving general payments from pharmaceutical companies are more likely to prescribe their drugs

Odds of Prescribing Drugs Up With Doc Receipt of Payments

Doctors who receive general payment for cancer drug more likely to prescribe drug marketed by company
Polypharmacy is associated with poorer cognitive and physical capability even after adjustment for disease burden

Polypharmacy Linked to Poorer Cognitive, Physical Capability

Stronger negative associations for participants with polypharmacy at age 60 to 64 years and at 69 years
Most people in the United States are unaware of national cancer drug shortages

Most Patients Are Unaware of Drug Cancer Shortages

Majority say they want to know about even minor consequences of cancer drug substitutions
Sirolimus may be beneficial for patients with diffuse idiopathic pulmonary neuroendocrine cell hyperplasia

Sirolimus May Be Beneficial in DIPNECH Syndrome

Beneficial effects seen for three women with diffuse idiopathic pulmonary neuroendocrine cell hyperplasia
Myocarditis in patients treated with immune checkpoint inhibitors may be more common than previously thought

Myocarditis Rare Side Effect of Immune Checkpoint Inhibitors

Myocarditis with ICIs may be more common than initially thought; responds to higher steroid dosages
Children of first-cousin consanguineous parents are more likely to be in receipt of antidepressant or anxiolytic medications and antipsychotic medications

Mood Disorders Up for Children of Consanguineous Parents

Increased odds of mental health issues and needing antidepressant, anxiolytic, antipsychotic medications
There is considerable variation in the quality of free-text patient directions in electronic prescriptions

Variations Identified in Free-Text Directions in E-Prescriptions

However, more than half of all prescriber's patient directions could be categorized into 25 concepts