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For patients with noncancer pain and opioid-induced constipation

Naloxegol Has No Effect on Opioid Dose in Opioid-Tied Constipation

Centrally-mediated analgesia was maintained during treatment with naloxegol in noncancer pain, OIC
Vitamin D deficiency may be associated with increased neuropathic pain in patients with rheumatoid arthritis

Vitamin D Deficiency Tied to Neuropathic Pain

Findings among patients diagnosed with rheumatoid arthritis
A 10-mL 1 percent lidocaine paracervical nerve block reduces pain during intrauterine device insertion

Lidocaine Nerve Block Reduces Pain During IUD Insertion

Pain score lower among patients who receive lidocaine than those who receive placebo
Electrotherapy and acupuncture seem to be beneficial for pain management after total knee arthroplasty

Electrotherapy, Acupuncture Ease Post Knee Arthroplasty Pain

Meta-analysis shows drop in use of opioids for electrotherapy; delayed opioid use with acupuncture
Cannabis may alleviate neuropathic pain

Review: Cannabis May Alleviate Neuropathic Pain

Second review shows no benefit for plant-based cannabis preparation versus nonuse for PTSD
Sensory over-responsiveness in otherwise healthy subjects is associated with a pro-nociceptive state

Higher Pain Expression Tied to Pro-Nociceptive State

With sensory over-responsiveness, daily non-painful stimuli felt more intensely
Substantially higher opioid prescribing rates persist among cancer survivors

Opioid Prescription Rates Higher in Cancer Survivors

Higher prescribing rates persist even years after cancer diagnosis

Are Clinicians Overprescribing Gabapentinoids for Pain?

Non-trivial side effects, no robust evidence for off-label use of gabapentinoids for other types of pain
For patients with chronic fatigue syndrome/fibromyalgia or rheumatoid arthritis

Morphine Effects Similar to Placebo in Rheumatoid Arthritis

Anti-hyperalgesic effects of morphine also similar to placebo in chronic fatigue/fibromyalgia
Postoperative pain is frequently underrated when assessed by nursing staff on wards

Post-Op Pain May Often Be Underrated by Inpatient Staff

Cross sectional data comparison of pain assessment showed large gap of underrated pain