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A first opioid lawsuit is targeting pharmacy benefit managers

First Opioid Lawsuit Targeting Pharmacy Benefit Managers

First lawsuit mentions three largest PBMs; PBMs likely to be increasingly targeted in litigation
Heavy use of opiates among patients with inflammatory bowel diseases is tied to increased risk of premature all-cause death

Opiate Use Linked to Early Mortality in IBD Patients

Heavy use in Crohn's, heavy or moderate use in ulcerative colitis tied to increased risk of death
Messages relating to safe storage and disposal of prescription opioids are inconsistent and are often not included on package insert information

Opioid Packaging Often Lacks Info on Safe Storage, Disposal

Instructions for safe disposal of unused opioid medications often inconsistent, infrequent, or absent
In adults age 50 or older

Education, Depression, Pain Associated With Opioid Misuse

Illicit drug use also a significant predictor of misuse in adults ≥50 taking opioids for chronic pain
State implementation of medical marijuana laws is associated with a reduction in the rate of opioid prescribing

Marijuana Legalization May Reduce Opioid Use

Implementation of adult-use marijuana laws linked to 6.38 percent lower rate of opioid prescribing
From 2015 to 2016

CDC: Overdose Deaths Up Across Drug Categories in 2015 to 2016

Of 63,632 drug overdose deaths in 2016, 66.4 percent involved an opioid
Preoperative chronic opioid use is associated with poor outcomes and continued dependence after posterior lumbar fusion

Pre-Op Chronic Opioid Use Ups Poor Outcomes Post Spinal Fusion

Preoperative opioid use tied to complications, ER visits, readmission, adverse events, increased costs
Pharmacists should be aware that they are expected to take steps to make sure opioid prescriptions are written for legitimate medical purposes

Pharmacists Have Responsibility to Check Opioid Rx Are Legitimate

Pharmacists should document their efforts to make sure rx are written for legitimate medical purposes
County-level economic and other social conditions explain the geographic disparities in overdose rates across the country

Geographic, Social Variances Tied to Higher Drug-Related Mortality

Economic, social conditions, and family distress tied to higher drug mortality rates
Adolescents with pre-existing mental health conditions and treatments are more likely to receive any opioid and to transition to long-term opioid therapy

Opioid Receipt Up for Teens With Mental Health Conditions

Teens with pre-existing mental health conditions, tx more likely to transition to long-term opioid use