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Neuronal growth hormone secretagogue receptor is involved in regulating energy metabolism

Neuronal GHS-R Involved in Regulating Energy Metabolism

Deletion of neuronal Ghsr in mice almost completely prevents diet-induced obesity
The body mass index linked to the lowest rate of all-cause early mortality is rising

Excess Weight May Not Equal Early Mortality After All

BMI linked to lowest rate of all-cause early death up by more than three units since 1970s
For patients with obesity and type 2 diabetes

Exenatide Reduces Liver Fat in Type 2 Diabetes With Obesity

Reduction in epicardial adipose tissue and liver fat content with exenatide versus reference treatment
Psoriasis may be linked to excess weight and type 2 diabetes

Research Finds Link Between Psoriasis, Obesity, T2DM

A genetic link is one theory for the possible association, researchers say
Examining national data from 1999 through 2014

Severe Childhood Obesity Still on the Rise in the United States

Treatment for these 4.5 million children is urgently needed
Supplementation with polyphenols does not strongly protect against cardiovascular diseases among patients with metabolic syndrome

Dietary Polyphenols Don’t Provide Much CV Benefit in Metabolic Sx

Findings from review assessing supplementation in metabolic syndrome patients
For patients with type 2 diabetes

Interrupting Prolonged Sitting Beneficial in Type 2 Diabetes

Brief bouts of light-intensity walking, simple resistance activities improve cardiometabolic factors
Inhibition of phosphodiesterase-4

PDE4 Inhibition Promising Tx for Metabolic Disorders

Derangement of PDE4-cAMP signaling is pathophysiologically relevant in metabolic disorders
Recommendations have been issued for the use of direct oral anticoagulants in obese patients; the guideline was published online March 22 in the Journal of Thrombosis and Haemostasis.

Guidance Issued on Use of Direct Oral Anticoagulants in Obese

DOAC use not recommended for patients with BMI >40 kg/m² and weight >120 kg
Overweight/obese men receiving a dose of oxytocin nasal spray act less impulsively and exert more control over their behavior compared with men receiving placebo

ENDO: Oxytocin Shows Promise in Overweight/Obese Men

Men receiving nasal spray of oxytocin act less impulsively and exert more control over behavior