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Intestinal glucose stimulation has an anti-incretin effect

Intestinal Glucose Stimulation Has Anti-Incretin Effect

Insulin sensitivity lower during oral versus IV glucose administration; difference amplified in obese
Metabolically healthy obese individuals have increased risk of coronary heart disease

Cardiac Disease Events Up in Metabolically Healthy Obese

Increased risks of coronary heart disease, cerebrovascular disease, heart failure
Stress is associated with impaired sleep and increased emotional rewarding of palatable foods

Role of Stress, Sleep Highlighted in Study of Obesity

Stress linked to impaired sleep, increased emotional rewarding of palatable foods, leading to obesity
There is organ-dependent crosstalk between adipose tissue and carcinomas in various organs

Crosstalk Identified Between Adipose Tissue, Carcinomas

Organ-dependent crosstalk identified via VEGF, IL6, TNFα, and other mechanisms
For adults with obesity

Addition of Exercise to Weight Loss Ups Mitochondrial Capacity

Improved mitochondrial respiratory capacity for older obese adults with weight loss + exercise
Given population obesity trends

Demand for Liver Transplant for NASH Set to Continue Rising

Increase in obesity prevalence strongly linked to liver transplant waitlist additions nine years later
Higher dietary energy density (the ratio of energy intake to food weight) is associated with increased risk of obesity-related cancers among normal-weight women

Dietary Energy Density May Up Risk of Obesity-Linked Cancers

DED linked to 10 percent increase of any obesity-related cancer among normal-weight women
For patients undergoing cardiac surgery

Use of ICU Resources After Cardiac Surgery Upped by Obesity

Increasing obesity tied to greater likelihood of prolonged ICU stay and ventilation, ICU readmission

APA: Medical Discrimination Based on Size Stresses Patients

Assuming weight is responsible for, related to presenting complaints can result in misdiagnosis
Obesity even in adolescence may raise the odds for colon and rectal cancers in adulthood

Obesity in Teens Ups Colon, Rectal Cancer Risk in Adulthood

Concerns are growing about weight's impact on development of chronic disease, researchers say