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American Society of Nephrology, Oct. 23-28

The Annual Meeting of the American Society of Nephrology, Kidney Week 2018 Kidney Week, the annual meeting of the American Society of Nephrology,...
Prescription of antibiotics and acid-suppressing medications in early childhood is associated with an increased risk for obesity

Antibiotics, Acid Suppressants in Infancy May Up Obesity Risk

Prescription of antibiotics, acid-suppressing meds in first two years of life linked to childhood obesity
High childhood body mass index is strongly correlated with slipped capital femoral epiphysis

Strong Link for Peds Obesity, Slipped Capital Femoral Epiphysis

Children with severe obesity at 5 to 6 years and 11 to 12 years old have increased risk for SCFE
Early-onset asthma and wheezing may contribute to an increased risk of developing obesity later in childhood

Asthma May Raise Obesity Risk Later in Childhood

3- to 4-year-olds with active asthma, wheezing have increased risk of obesity by age 8
In adults with moderate obesity and either impaired glucose tolerance or recently diagnosed mild type 2 diabetes

Gastric Banding, Metformin Similar for Improving Glycemia

Both preserved β-cell function in obese adults with impaired glucose tolerance, mild T2DM
For patients with severe obesity and type 2 diabetes

Bariatric Sx Cuts Macrovascular Complications in Obesity, T2DM

Lower composite incidence of macrovascular events, lower incidence of coronary artery disease at 5 years
Greater weight gain in early childhood often carries over to overweight and obesity in adolescence

Childhood Obesity Persists Into Adolescence

Among obese teens, most rapid weight gain happened in childhood between ages 2 and 6
Lorcaserin reduces the risk for diabetes in obese or overweight patients with prediabetes or without diabetes and reduces hemoglobin A1c among those with diabetes

Lorcaserin Beneficial for Diabetes in Overweight, Obese

Lorcaserin reduces risk for diabetes for those with prediabetes, without diabetes; reduces HbA1c
Lorcaserin facilitates sustained weight loss without increasing the rate of major cardiovascular events among overweight or obese patients

Lorcaserin Facilitates Weight Loss in Overweight, Obese

Increased weight loss versus placebo with no rise in rate of extended major cardiovascular events
For overweight/obese veterans with prediabetes

Participation Up With Online Diabetes Prevention Program

But weight loss no different for online, in-person DPP for obese/overweight veterans with prediabetes