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Tag: Heart / Stroke-Related: Stroke

For patients with atrial fibrillation at moderate to high risk of stroke

DAPT Use Variable in Patients With A-Fib at Risk of Stroke

Dual antiplatelet therapy used in variable manner; most patients remain on study drug after PCI
For insulin-resistant patients with recent ischemic stroke or transient ischemic attack

Pioglitazone Cuts Diabetes Risk After Ischemic Stroke, TIA

Findings for patients with recent ischemic stroke/TIA and insulin resistance, but no history of diabetes
For patients in the Apixaban for Reduction of Stroke and Other Thromboembolic Complications in Atrial Fibrillation trial

Usual Apixaban Dosing OK With One Dose-Reduction Criterion

5 mg apixaban twice daily deemed safe, appropriate for those with one criterion in ARISTOTLE trial
The odds of surviving a stroke are slightly better for patients treated at hospitals with primary stroke centers

Primary Stroke Centers Have Slight Survival Edge

Study finds small advantage, but only if patient gets there within 90 minutes
For patients with minor ischemic stroke or transient ischemic attack

Clopidogrel Plus Aspirin Good for Noncarriers of CYP2C19 Variants

Reduction in risk of new stroke for clopidogrel plus aspirin in those not carrying loss-of-function alleles
Statins could significantly reduce the risk of infection in stroke patients

Statins Could Reduce Risk of Infection in Stroke Patients

Meds may have anti-inflammatory properties that help the body respond to infection
Circadian rhythm disruption associated with shifted light:dark cycles exacerbates stroke outcomes in a rat model

Shift Work ‘Unwinds’ Body Clock, May Lead to More Severe Stroke

Circadian rhythm disruption may interact with sex to modulate pathological effect of stroke
Injecting modified

Stem Cells Can Restore Motor Function in Stroke Patients

Experimental procedure helps restore movement even a year after stroke
For children with arterial ischemic stroke

Hyperglycemia Tied to Outcomes in Pediatric Stroke

Infarct volume, hyperglycemia linked to poor neurological outcome in arterial ischemic stroke
Treatment with sulfonylureas (ATP-sensitive potassium [KATP] channel blockers) may inhibit the neuroprotective effects of KATP channel activation and increase the risk of stroke

Sulfonylureas May Inhibit KATP Channel Neuroprotection

Treatment with sulfonylureas may increase the risk of stroke mortality in patients with type 2 diabetes