Tag: Genetics
Internists Key to Identifying Need for Genetic Counseling for Cancer
Complexity of genetic counseling for multigene testing has increased considerably
70-Gene Signature Impacts Treatment Decisions in Breast CA
70-GS linked to change in treatment decisions for intermediate-risk patients based on 21-gene assay
Locus ID’d That Links Comorbid Alcohol Dependence, Depression
Robust association identified for SEMA3A locus in African American participants in two samples
Concerns Surround Use of Direct-to-Consumer Genetic Testing
Issues include limited knowledge about available tests, difficulty interpreting results, lack of oversight
HER3 Linked to Improved Survival With Panitumumab
Addition of panitumumab to irinotecan tied to improved survival in RAS wt advanced colorectal CA
Smoking Alters Genetic Relationship with Parkinson’s
Smoking, HLA-DRB1 may be involved in common pathways, possibly neuroinflammation
Gene Expression Assay Classifies Diffuse Large B-Cell Lymphoma
Assay assesses expression of 21 markers, classifies most samples into expected subtype
Genetic Variant Tied to Prostate Cancer Outcomes
Time to metastasis, length of survival vary by number of HSD3B1 (1245C) variant alleles
Antisocial Behavior May Be Highly Polygenic
Promising loci that have sex-discordant associations with ASB identified
Scientists Support Genome Editing to Prevent Disease
Majority of survey respondents support gene editing to treat diseases but not human enhancement
