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Tag: Diabetes: Type II

Compared to placebo

Pioglitazone Associated With Lower Blood Leptin in Diabetes

In T2DM, leptin levels are lower with pioglitazone than placebo but not oral antidiabetic drugs
For healthy adults and individuals with well-controlled type 2 diabetes

DPP-4 Inhibitor Has Dissociated Effects on β-Cell Function

Single dose of sitagliptin linked to increases in standardized insulin secretion, active GIP, GLP-1
Intensive blood pressure lowering may similarly decrease cardiovascular events in both patients with and patients without type 2 diabetes mellitus

Intensive BP Goals Reduce Risk of Cardiovascular Events

Benefits similar in patients with and without type 2 diabetes
For patients with type 2 diabetes mellitus undergoing non-cardiac surgery

Pre-Op Liraglutide Cuts Post-Op Plasma Glucose in T2DM

Preoperative administration of liraglutide linked to lower post-op glucose, increase in pre-op nausea
The TIMI (Thrombolysis in Myocardial Infarction) Risk Score for Secondary Prevention is an accurate predictor of atherothrombotic disease among patients with type 2 diabetes

Expanded TIMI Risk Score Deemed Practical in Diabetes

Atherothrombotic disease risk assessment based upon 10 readily available clinical variables
Stricter glycemic control during short-term intensive insulin therapy for newly diagnosed type 2 diabetes patients is associated with a higher likelihood of remission at one year

Stricter Short-Term Glycemic Control May Increase Remission

Findings among newly diagnosed diabetes patients undergoing short-term intensive insulin therapy
Patients with diabetes report worse quality of life with more intensified treatment

Measuring Quality of Life Important With Diabetes Tx

Predictors of patient-reported outcomes vary by outcome examined
Individuals with prior Roux-en-Y gastric bypass have blunted β-cell sensitivity to changes in glycemia

β-Cell Sensitivity to Glucose Impaired After Gastric Bypass

Individuals with prior Roux-en-Y gastric bypass have reduced β-cell glucose sensitivity
A community-based program improves quality of life and self-management in older adults with type 2 diabetes mellitus and comorbidities

Program Aids Quality of Life for Older Adults With T2DM

Intervention includes in-home nurse visits, wellness program, care coordination
A new once-weekly diabetes medication that lowers blood glucose and also helps patients lose weight has been approved by the U.S. Food and Drug Administration.

FDA Approves Ozempic for Type 2 Diabetes

Novo Nordisk drug also found to help with weight loss