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Tag: Diabetes: Type I

For patients with type 1 diabetes undergoing a first multivessel revascularization

CABG May Be Best for Multivessel Revascularization in T1DM

Increased risks of coronary heart disease mortality, MI, repeat revascularization with PCI
Diabetes in infancy has different characteristics depending on mutation subtype

Characteristics of Diabetes in Infancy Explored

Overall frequency of diabetic ketoacidosis 66.2 percent; odds increase with age at diagnosis
For patients newly diagnosed with type 1 diabetes

Peptide Immunotx Well Tolerated in New-Onset Type 1 Diabetes

No decline in C-peptide with peptide immunotherapy; no change in insulin use over 12 months
For adolescents with type 1 diabetes

Exercise Training Improves Left Ventricular Function in T1DM

Improvement in aerobic capacity and stroke volume lower for teens with T1DM than control healthy teens
Celiac disease is a common comorbidity in young people with type 1 diabetes

International Variation in Prevalence of Celiac in T1DM

Overall, 3.5 percent of children had biopsy-confirmed CD; prevalence was higher for girls than boys
Parents of children at increased genetic risk for type 1 diabetes and with positive islet autoantibody testing have increased anxiety

Increased Parental Anxiety With Increased Diabetes Risk

Anxiety up for parents of children at increased genetic risk with positive islet autoantibody testing
For children

Genetic, Environmental Exposure Tied to Islet Autoantibodies

Link for male sex; father, sibling as diabetic proband; weight at 12 months with insulin autoantibodies
Patients with remaining endogenous β-cell function after a decade of living with type 1 diabetes tend to have much higher levels of interleukin-35 than other patients with long-standing type 1 diabetes

T1DM Patients With Active β-Cell Function Differ Immunologically

Findings for patients with remaining endogenous β-cell function after 10 or more years of T1DM
Serum levels of soluble receptor for advanced glycation end products are associated with the risk of developing incident diabetic nephropathy in individuals with type 1 diabetes

sRAGE Linked to Risk of Incident Diabetic Nephropathy

Independent link seen for soluble receptor for advanced glycation end products, but not for CML
Diabetic ketoacidosis during pregnancy poses risk for the fetus during and after the event

Diabetic Ketoacidosis Poses Fetal Risk During/After Event

Risk of fetal demise increased with maternal ICU admission and higher serum osmolality during DKA